« Previous
Next »
Surgery
Volume 145, Issue 5
, Pages 550-557
, May 2009
Adiponectin deficiency is associated with severe polymicrobial sepsis, high inflammatory cytokine levels, and high mortality
References
- . The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med. 2003;348:1546–1554
- . Septic shock. Lancet. 2005;365:63–78
- . The influence of gender on human innate immunity. Surgery. 2005;138:275–282
- . Obesity-related excess mortality rate in an adult intensive care unit: a risk-adjusted matched cohort study. Crit Care Med. 2004;32:998–1003
- Predisposing factors for hypoglycemia in the intensive care unit. Crit Care Med. 2006;34:96–101
- . Gender and susceptibility to sepsis following trauma. Endocr Metab Immune Disord Drug Targets. 2006;6:127–135
- Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun. 1999;257:79–83
- Implications of plasma concentrations of adiponectin in patients with coronary artery disease. Heart. 2004;90:528–533
- A novel cellular marker of insulin resistance and early atherosclerosis in human is related to impaired fat cell differentiation and low adiponectin. FASEB J. 2003;17:1434–1440
- Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. Arterioscler Thromb Vasc Biol. 2000;20:1595–1599
- Adiponectin, a new member of the family of soluble defense collagens, negatively regulates the growth of myelomonocytic progenitors and the functions of macrophages. Blood. 2000;96:1723–1732
- Diet-induced insulin resistance in mice lacking adiponectin/ACRP30. Nat Med. 2002;8:731–737
- Role of adiponectin vascular stenosis. The missing link of adipo-vascular axis. J Biol Chem. 2002;277:37487–37491
- . Human adiponectin binds to bacterial lipopolysaccharide. Biochem Biophys Res Commun. 2006;341:108–115
- Circulating concentrations of adiponectin, an endogenous lipopolysaccharide neutralizing protein, decrease in rats with polymicrobial sepsis. J Surg Res. 2006;134:348–353
- PPARγ ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein. Diabetes. 2001;50:2094–2099
- Statin reverses reduction of adiponectin receptor expression in infarcted heart and in TNF-alpha-treated cardiomyocytes in association with improved glucose uptake. Am J Physiol Heart Circ Physiol. 2007;293:H3490–H3497
- Nocturnal reduction in circulating adiponectin concentrations related to hypoxic stress in severe obstructive sleep apnea-hypopnea syndrome. Am J Physiol Endocrinol Metab. 2008;294:E778–E784
- . Effect of sepsis on tissue adenine nucleotide levels. Surgery. 1979;85:205–211
- . An automated analysis system of Limulus amebocyte lysate (LAL)-endotoxin reaction kinetics using turbidimetric kinetic assay. Chem Pharm Bull (Tokyo). 1988;36:3012–3019
- . The role of bacterial translocation on neutrophil activation during hemorrhagic shock in rats. Shock. 2001;16:59–63
- . An exaggerated inflammatory response after CLP correlates with a negative outcome. J Surg Res. 2005;125:88–93
- Plasma cytokine measurements augment prognostic scores as indicators of outcome in patients with severe sepsis. Shock. 2005;23:488–493
- . Plasma cytokine and endotoxin levels correlate with survival in patients with the sepsis syndrome. Ann Intern Med. 1993;119:771–778
- . Effect of genomic polymorphisms on the course of sepsis: is there a concept for gene therapy?. J Am Soc Nephrol. 2001;12:S60–S64
- Inflammatory cytokines, C reactive protein, and procalcitonin as early predictors of necrosis infection in acute necrotizing pancreatitis. Surgery. 2003;133:257–262
- Association of hypoadiponectinemia with coronary artery disease in men. Arterioscler Thromb Vasc Biol. 2003;23:85–89
- Genetic variation in the gene encoding adiponectin is associated with an increased risk type 2 diabetes in the Japanese population. Diabetes. 2002;51:536–540
- . Cecal ligation and puncture as a model of sepsis in the rat: influence of the puncture size on mortality, bacteremia, endotoxemia and tumor necrosis factor alpha levels. Eur Surg Res. 2001;33:77–79
- Investigation into the interaction of recombinant human serum albumin with Re-lipopolysaccharide and lipid A. J Endotoxin Res. 2002;8:115–126
- Reconstituted high-density lipoprotein attenuates organ injury and adhesion molecule expression in a rodent model of endotoxin shock. Shock. 2003;20:551–557
- . Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS. J Exp Med. 1994;180:1025–1035
- . Implication of Toll-like receptor and tumor necrosis factor alpha signaling in septic shock. Shock. 2005;24:206–209
- Differences in arterial and mixed venous IL-6 levels: the lungs as a source of cytokine storm in sepsis. Surgery. 2001;130:748–751
- . Sepsis and endotoxemia stimulate intestinal interleukin-6 production. Surgery. 1995;118:336–342
- . Adiponectin and metabolic syndrome. Arterioscler Thromb Vasc Biol. 2004;24:29–33
- . Adiponectin differentially regulates cytokines in porcine macrophages. Biochem Biophys Res Commun. 2004;316:924–929
- Correlation of the adipocyte-derived protein adiponectin with insulin resistance index and serum high-density lipoprotein-cholesterol, independent of body mass index, in the Japanese population. Clin Sci (Lond). 2002;103:137–142
- . Low serum level of high-density lipoprotein cholesterol is a poor prognostic factor for severe sepsis. Crit Care Med. 2005;33:1688–1693
- . Hyperglycemia enhances the cytokine production and oxidative responses to a low but not high dose of endotoxin in rats. Crit Care Med. 2005;33:1084–1089
- An adipocyte-derived plasma protein, adiponectin, adheres to injured vascular walls. Horm Metab Res. 2000;32:47–50
- . Endothelial E- and P-selectin expression in iNOS-deficient mice exposed to polymicrobial sepsis. Am J Physiol Gastrointest Liver Physiol. 2001;280:G291–G297
- . Hormonal regulation of adiponectin gene expression in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2002;290:1084–1089
- . Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS Lett. 2001;507:142–146
- Adiponectin gene expression and secretion is inhibited by interleukin-6 in 3T3-L1 adipocytes. Biochem Biophys Res Commun. 2003;301:1045–1050
- Adiponectin deficiency promotes endothelial activation and profoundly exacerbates sepsis-related mortality. Am J Physiol Endocrinol Metab. 2008;295:E658–E664
- . Transcriptional regulation of metabolism. Physiol Rev. 2006;86:465–514
- . Thiazolidinediones. N Engl J Med. 2004;351:1106–1118
- Evidence for a potent antiinflammatory effect of rosiglitazone. J Clin Endocrinol Metab. 2004;89:2728–2735
- . The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice. J Clin Invest. 2003;112:91–100
- . Nimodipine, a dihydropyridine-type calcium channel blocker, prevents alcoholic hepatitis caused by chronic intragastric ethanol exposure in the rat. Hepatology. 1996;24:391–397
- . The chronic consequences of severe sepsis. J Leukoc Biol. 2004;75:408–412
Y.U., H.T., T.S., and Y.E. contributed equally to this manuscript.
PII: S0039-6060(09)00072-5
doi: 10.1016/j.surg.2009.01.010
© 2009 Mosby, Inc. All rights reserved.
« Previous
Next »
Surgery
Volume 145, Issue 5
, Pages 550-557
, May 2009
