Women rule
Female animals tolerate trauma and hemorrhage better than male animals
AND
Estrogen has rapid nongenomic effects that protect organs from damage and attenuate insult–induced inflammation
MOREOVER
The survival deficit from trauma and hemorrhage produced in ovariectomized female animals is repaired with administration of exogenous estrogen
AND
Women survive injury, sepsis, and trauma-hemorrhage–induced hypoxemia/reperfusion better than men
THEREFORE
Women rule … in survival after trauma, thus, men would benefit from being more like women.
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PII: S0039-6060(09)00349-3
doi:10.1016/j.surg.2009.04.033
© 2010 Mosby, Inc. All rights reserved.
