Single center experience transplanting kidneys from deceased donors with terminal acute renal failure
Accepted 5 June 2009.
Background
Transplantation of kidneys from deceased donors with terminal acute renal failure (ARF) is uncommon.
Methods
We reviewed retrospectively our single-center experience with transplantation of ARF donor kidneys.
Results
From January 2007 through September 2008, we transplanted 25 kidneys from 17 ARF donors; 22 kidneys were from standard criteria donors. Mean donor age was 34 years. Mean admission and terminal donor serum creatinine values were 1.3 mg/dL and 3.1 mg/dL. All but 2 kidneys were placed on pump preservation; mean cold ischemia time was 27 hours. The recipient group had a mean age of 49 years and a mean waiting time of 24 months. Patient and graft survival rates were 100% and 92%, respectively, with a mean follow-up of 12 months. Delayed graft function occurred in 8 patients (32%), mean initial duration of stay was 6 days, 3 patients (12%) required re-operation, 3 patients (12%) had acute rejection, and 8 patients (32%) developed infections. Mean 1- and 12-month recipient serum creatinine and glomerular filtration rate values were 1.9 mg/dl (45 mL/min) and 1.5 mg/dl (50 mL/min), respectively.
Conclusion
Kidneys from deceased donors with terminal ARF have excellent short-term outcomes and represent another potential method to safely expand the donor pool.
Department of General Surgery, Wake Forest University School of Medicine, Winston-Salem, NC
Reprint requests: Robert J. Stratta, MD, Department of General Surgery, Wake Forest University School of Medicine, Medical Center Boulevard, Winston-Salem, NC 27157.
ABSTRACT