Surgery
Volume 146, Issue 4 , Pages 561-568 , October 2009

Does ductal carcinoma in situ accompanying invasive carcinoma affect prognosis?

  • Anees B. Chagpar, MD, MSc, MPH

      Affiliations

    • Department of Surgery, University of Louisville, Louisville, KY
    • Corresponding Author InformationReprint requests: Anees B. Chagpar, MD, 315 E. Broadway, Suite 312, Louisville, KY 40202.
    • ,
  • Kelly M. McMasters, MD, PhD

      Affiliations

    • Department of Surgery, University of Louisville, Louisville, KY
    • ,
  • Sunati Sahoo, MD

      Affiliations

    • Department of Pathology, University of Louisville, Louisville, KY
    • ,
  • Michael J. Edwards, MD

      Affiliations

    • Department of Surgery, University of Cincinnati, Cincinnati, OH

,Accepted 25 June 2009.

References 

  1. American Cancer Society. Breast Cancer Facts & Figures 2007-2008. Atlanta: American Cancer Society, Inc; 2007;
  2. Hofvind S, Sorum R, Thoresen S. Incidence and tumor characteristics of breast cancer diagnosed before and after implementation of a population-based screening-program. Acta Oncol. 2008;47:225–231
  3. Kuerer HM, Albarracin CT, Yang WT, et al. Ductal carcinoma in situ: state of the science and roadmap to advance the field. J Clin Oncol. 2009;27:279–288
  4. Erbas B, Provenzano E, Armes J, et al. The natural history of ductal carcinoma in situ of the breast: a review. Breast Cancer Res Treat. 2006;97:135–144
  5. Black MM, Zachrau RE, Hankey BF, et al. Prognostic significance of in situ carcinoma associated with invasive breast carcinoma. A natural experiment in cancer immunology?. Cancer. 1996;78:778–788
  6. Iakovlev VV, Arneson NC, Wong V, et al. Genomic differences between pure ductal carcinoma in situ of the breast and that associated with invasive disease: a calibrated aCGH study. Clin Cancer Res. 2008;14:4446–4454
  7. Castro NP, Osorio CA, Torres C, et al. Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma. Breast Cancer Res. 2008;10:R87
  8. Singletary SE, Allred C, Ashley P, et al. Revision of the American Joint Committee on Cancer staging system for breast cancer. J Clin Oncol. 2002;20:3628–3636
  9. Dillon MF, Maguire AA, McDermott EW, et al. Needle core biopsy characteristics identify patients at risk of compromised margins in breast conservation surgery. Mod Pathol. 2008;21:39–45
  10. Mai KT, Perkins DG, Mirsky D. Location and extent of positive resection margins and ductal carcinoma in situ in lumpectomy specimens of ductal breast carcinoma examined with a microscopic three-dimensional view. Breast J. 2003;9:33–38
  11. Dzierzanowski M, Melville KA, Barnes PJ, et al. Ductal carcinoma in situ in core biopsies containing invasive breast cancer: correlation with extensive intraductal component and lumpectomy margins. J Surg Oncol. 2005;90:71–76
  12. Jimenez RE, Bongers S, Bouwman D, et al. Clinicopathologic significance of ductal carcinoma in situ in breast core needle biopsies with invasive cancer. Am J Surg Pathol. 2000;24:123–128
  13. Kurniawan ED, Wong MH, Windle I, et al. Predictors of surgical margin status in breast-conserving surgery within a breast screening program. Ann Surg Oncol. 2008;15:2542–2549
  14. Logullo AF, Godoy AB, Mourao-Neto M, et al. Presence of ductal carcinoma in situ confers an improved prognosis for patients with T1N0M0 invasive breast carcinoma. Braz J Med Biol Res. 2002;35:913–919
  15. Matsukuma A, Enjoji M, Toyoshima S. Ductal carcinoma of the breast. An analysis of proportions of intraductal and invasive components. Pathol Res Pract. 1991;187:62–67
  16. Leong AS, Sormunen RT, Vinyuvat S, et al. Biologic markers in ductal carcinoma in situ and concurrent infiltrating carcinoma. A comparison of eight contemporary grading systems. Am J Clin Pathol. 2001;115:709–718
  17. Gupta SK, Douglas-Jones AG, Fenn N, et al. The clinical behavior of breast carcinoma is probably determined at the preinvasive stage (ductal carcinoma in situ). Cancer. 1997;80:1740–1745
  18. Moriya T, Silverberg SG. Intraductal carcinoma (ductal carcinoma in situ) of the breast. A comparison of pure noninvasive tumors with those including different proportions of infiltrating carcinoma. Cancer. 1994;74:2972–2978
  19. Mechera R, Viehl CT, Oertli D. Factors predicting in-breast tumor recurrence after breast-conserving surgery. Breast Cancer Res Treat. 2008;116:171–177

 Supported by an unrestricted educational grant from Schering-Plough and a grant from Orion Pharma.

PII: S0039-6060(09)00455-3

doi: 10.1016/j.surg.2009.06.039

Surgery
Volume 146, Issue 4 , Pages 561-568 , October 2009

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