Surgery
Volume 147, Issue 2 , Pages 204-211 , February 2010

Impact of lymphovascular invasion in patients with stage I gastric cancer

  • Chikara Kunisaki, MD, PhD

      Affiliations

    • Department of Surgery, Gastroenterological Center, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • Corresponding Author InformationReprint requests: Chikara Kunisaki, MD, PhD, Department of Surgery, Yokohama City University, 4-57, Urafune-cho, Minami-ku, Yokohama, 232-0024, Japan.
    • ,
  • Hirochika Makino, MD, PhD

      Affiliations

    • Department of Surgery, Gastroenterological Center, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Jun Kimura, MD

      Affiliations

    • Department of Surgery, Gastroenterological Center, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Ryo Takagawa, MD

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Takashi Kosaka, MD

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Hidetaka A. Ono, MD, PhD

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Hirotoshi Akiyama, MD, PhD

      Affiliations

    • Department of Gastroenterological Surgery, Yokohama City University, Graduate School of Medicine, Yokohama, Japan
    • ,
  • Tadao Fukushima, MD, PhD

      Affiliations

    • Department of Surgery, Yokosuka Kyosai Hospital, Yokosuka, Japan
    • ,
  • Yutaka Nagahori, MD, PhD

      Affiliations

    • Department of Surgery, Yokosuka Kyosai Hospital, Yokosuka, Japan
    • ,
  • Masazumiu Takahashi, MD, PhD

      Affiliations

    • Department of Surgery, Yokohama Municipal Hospital, Yokohama, Japan

,Accepted 28 August 2009.

References 

  1. Inoue M, Tsugane S. Epidemiology of gastric cancer in Japan. Postgrad Med J. 2005;81:419–424
  2. Miyahara R, Miwa Y, Matsuura T, Maeda O, Ando T, Ohmiya N, et al. Prevalence and prognosis of gastric cancer detected by screening in a large Japanese population: data from a single institute over 30 years. J Gastroenterol Hepatol. 2007;22:1435–1442
  3. Ono H, Kondo H, Gotoda T, Shirao K, Yamaguchi H, Saito D, et al. Endoscopic mucosal resection for treatment of early gastric cancer. Gut. 2001;48:225–229
  4. Gotoda T, Yamamoto H, Soetikno RM. Endoscopic submucosal dissection of early gastric cancer. J Gastroenterol. 2006;41:929–942
  5. Nakajima T. Gastric cancer treatment guidelines in Japan. Gastric Cancer. 2002;5:1–5
  6. Lo SS, Wu CW, Chen JH, Li AF, Hsieh MC, Shen KH, et al. Surgical results of early gastric cancer and proposing a treatment strategy. Ann Surg Oncol. 2007;14:340–347
  7. In:  Sobin LH,  Wittekind CH editor. TNM: classification of malignant tumours. 6th ed.. New York: Wiley-Liss; 2002;
  8. Japanese Gastric Cancer Association. Japanese Classification of Gastric Carcinoma. Second Edition. Gastric Cancer. 1998;1:10–24
  9. Shimizu S, Uchiyama A, Mizumoto K, Morisaki T, Nakamura K, Shimura H, et al. Laparoscopically assisted distal gastrectomy for early gastric cancer: is it superior to open surgery?. Surg Endosc. 2000;14:27–31
  10. Lee JH, Han HS, Lee JH. A prospective randomized study comparing open vs laparoscopy-assisted distal gastrectomy in early gastric cancer. Surg Endosc. 2005;19:168–173
  11. Liu C, Zhang R, Lu Y, Li H, Lu P, Yao F, et al. Prognostic role of lymphatic vessel invasion in early gastric cancer: a retrospective study of 18 cases. Surg Oncol. 2008;Nov 28 [Epub ahead of print]
  12. Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Ono H, et al. Therapeutic strategy for patients with pN0 gastric carcinoma. J Surg Oncol. 2006;94:212–219
  13. Li C, Kim S, Lai JF, Oh SJ, Hyung WJ, Choi WH, et al. Risk factors for lymph node metastasis in undifferentiated early gastric cancer. Ann Surg Oncol. 2008;15:764–769
  14. Dicken BJ, Graham K, Hamilton SM, Andrews S, Lai R, Listgarten J, et al. Lymphovascular invasion is associated with poor survival in gastric cancer. An application of gene-expression and tissue array techniques. Ann Surg. 2006;243:64–73
  15. Kunisaki C, Shimada H, Nomura M, Matsuda G, Otsuka Y, Ono H, et al. Surgical outcomes of serosa-negative advanced gastric carcinoma. Anticancer Res. 2004;24:3169–3176
  16. Yokota T, Kunii Y, Saito T, Teshima S, Yamada Y, Iwamoto K, et al. Prognostic factors of gastric cancer tumours of less than 2 cm in diameter: rationale for limited surgery. Eur J Surg Oncol. 2002;28:209–213
  17. Sakuramoto S, Sasako M, Yamaguchi T, Kinoshita T, Fujii M, Nashimoto A, et al. for the ACTS-GC Group. Adjuvant chemotherapy for gastric cancer with S-1, an oral fluoropyrimidine. N Engl J Med. 2007;357:1810–1820

PII: S0039-6060(09)00523-6

doi: 10.1016/j.surg.2009.08.012

Surgery
Volume 147, Issue 2 , Pages 204-211 , February 2010

Article Tools

* Image Usage & Resolution