Surgery
Volume 148, Issue 1 , Pages 110-118 , July 2010

Postischemic poly (ADP-ribose) polymerase (PARP) inhibition reduces ischemia reperfusion injury in a hind-limb ischemia model

  • Robert S. Crawford, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • Hassan Albadawi, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • Marvin D. Atkins, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • John E. Jones, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • Hyung-Jin Yoo, MA

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
  • ,
  • Mark F. Conrad, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • W. Gerald Austen Jr., MD

      Affiliations

    • Division of Plastic and Reconstructive Surgery of the General Surgical Services, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
  • ,
  • Michael T. Watkins, MD

      Affiliations

    • Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Boston, MA
    • Harvard Medical School, Boston, MA
    • Corresponding Author InformationReprint requests: Michael T. Watkins, MD, Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, 15 Parkman Street, WAC 440, Boston, MA 02114.

,Accepted 7 December 2009.

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 Supported by the Pacific Vascular Research Foundation, the American Diabetes Association, the Geneen Fund at the Massachusetts General Hospital, and Grant 1R01AR055843 from the National Institutes of Health.

PII: S0039-6060(09)00798-3

doi: 10.1016/j.surg.2009.12.006

Surgery
Volume 148, Issue 1 , Pages 110-118 , July 2010