Surgery
Volume 148, Issue 3 , Pages 532-537 , September 2010

Correlation between indeterminate aspiration cytology and final histopathology of thyroid neoplasms

  • Tony Pang, MBBS

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
  • ,
  • Catharina Ihre-Lundgren, MD, PhD

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
  • ,
  • Anthony Gill, MD, FRCPA

      Affiliations

    • Department of Pathology, University of Sydney, Sydney Australia
  • ,
  • Todd McMullen, MD, PhD

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
  • ,
  • Mark Sywak, MD, FRACS

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
  • ,
  • Stan Sidhu, PhD, MD, FRACS

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
  • ,
  • Leigh Delbridge, MD, FRACS

      Affiliations

    • University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, Australia
    • Corresponding Author InformationReprint requests: Leigh Delbridge, MD, FRACS, University of Sydney Endocrine Surgery Unit, Wallace Freeborn Building, Royal North Shore Hospital, St Leonards 2065 NSW, Australia.

,Accepted 21 January 2010.

References 

  1. Hegedus L. Clinical practice. The thyroid nodule. N Engl J Med. 2004;351:1764–1771
  2. Brander A, Viikinkoski P, Nickels J, Kivisaari L. Thyroid gland: US screening in a random adult population. Radiology. 1991;181:683–687
  3. Mortensen JD, Woolner LB, Bennett WA. Gross and microscopic findings in clinically normal thyroid glands. J Clin Endocrinol Metab. 1955;15:1270–1280
  4. Delbridge L. Solitary thyroid nodule: current management. ANZ J Surg. 2006;76:381–386
  5. Gharib H, Papini E. Thyroid nodules: clinical importance, assessment, and treatment. Endocrinol Metab Clin North Am. 2007;36:707–735vi
  6. Ravetto C, Colombo L, Dottorini ME. Usefulness of fine-needle aspiration in the diagnosis of thyroid carcinoma: a retrospective study in 37,895 patients. Cancer. 2000;90:357–363
  7. Greenblatt DY, Woltman T, Harter J, Starling J, Mack E, Chen H. Fine-needle aspiration optimizes surgical management in patients with thyroid cancer. Ann Surg Oncol. 2006;13:859–863
  8. Cai XJ, Valiyaparambath N, Nixon P, Waghorn A, Giles T, Helliwell T. Ultrasound-guided fine needle aspiration cytology in the diagnosis and management of thyroid nodules. Cytopathology. 2006;17:251–256
  9. Morgan JL, Serpell JW, Cheng MS. Fine-needle aspiration cytology of thyroid nodules: how useful is it?. ANZ J Surg. 2003;73:480–483
  10. Cheung YS, Poon CM, Mak SM, Suen MW, Leong HT. Fine-needle aspiration cytology of thyroid nodules–how well are we doing?. Hong Kong Med J. 2007;13:12–15
  11. Mazeh H, Beglaibter N, Prus D, Ariel I, Freund HR. Cytohistologic correlation of thyroid nodules. Am J Surg. 2007;194:161–163
  12. Yang J, Schnadig V, Logrono R, Wasserman PG. Fine-needle aspiration of thyroid nodules: a study of 4703 patients with histologic and clinical correlations. Cancer. 2007;111:306–315
  13. Gharib H, Goellner JR. Fine-needle aspiration biopsy of the thyroid: an appraisal. Ann Intern Med. 1993;118:282–289
  14. Sangalli G, Serio G, Zampatti C, Bellotti M, Lomuscio G. Fine needle aspiration cytology of the thyroid: a comparison of 5469 cytological and final histological diagnoses. Cytopathology. 2006;17:245–250
  15. In:  De Lellis R,  Lloyd RV,  Heitz PU,  Eng C editor. Pathology and genetics of tumours of endocrine organs. WHO classification of tumours. Vol. 8:Lyon (France): IRAC Press; 2004;
  16. Hirokawa M, Carney JA, Goellner JR, DeLellis RA, Heffess CS, Katoh R, et al. Observer variation of encapsulated follicular lesions of the thyroid gland. Am J Surg Pathol. 2002;26:1508–1514
  17. Lloyd RV, Erickson LA, Casey MB, Lam KY, Lohse CM, Asa SL, et al. Observer variation in the diagnosis of follicular variant of papillary thyroid carcinoma. Am J Surg Pathol. 2004;28:1336–1340
  18. Baloch ZW, Livolsi VA. Follicular-patterned lesions of the thyroid: the bane of the pathologist. Am J Clin Pathol. 2002;117:143–150
  19. Renshaw AA, Gould EW. Why there is the tendency to “overdiagnose” the follicular variant of papillary thyroid carcinoma. Am J Clin Pathol. 2002;117:19–21
  20. Kapur U, Wojcik EM. Follicular neoplasm of the thyroid–vanishing cytologic diagnosis?. Diagn Cytopathol. 2007;35:525–528
  21. Tyler DS, Winchester DJ, Caraway NP, Hickey RC, Evans DB. Indeterminate fine-needle aspiration biopsy of the thyroid: identification of subgroups at high risk for invasive carcinoma. Surgery. 1994;116:1054–1060
  22. Tuttle RM, Lemar H, Burch HB. Clinical features associated with an increased risk of thyroid malignancy in patients with follicular neoplasia by fine-needle aspiration. Thyroid. 1998;8:377–383
  23. Raber W, Kaserer K, Niederle B, Vierhapper H. Risk factors for malignancy of thyroid nodules initially identified as follicular neoplasia by fine-needle aspiration: results of a prospective study of one hundred twenty patients. Thyroid. 2000;10:709–712
  24. Kim JW, Park IS, Kim BM, Kim YM, Chu YC, Cho YU. The clinical significance of atypia in thyroid fine-needle aspiration. Eur Arch Otorhinolaryngol. 2007;264:1053–1057
  25. DeMay RM. Follicular lesions of the thyroid. W(h)ither follicular carcinoma?. Am J Clin Pathol. 2000;114:681–683
  26. LiVolsi VA, Asa SL. The demise of follicular carcinoma of the thyroid gland. Thyroid. 1994;4:233–236
  27. Albores-Saavedra J, Henson DE, Glazer E, Schwartz AM. Changing patterns in the incidence and survival of thyroid cancer with follicular phenotype–papillary, follicular, and anaplastic: a morphological and epidemiological study. Endocr Pathol. 2007;18:1–7
  28. Chan JK. Strict criteria should be applied in the diagnosis of encapsulated follicular variant of papillary thyroid carcinoma. Am J Clin Pathol. 2002;117:16–18
  29. Hunt JL, Dacic S, Barnes EL, Bures JC. Encapsulated follicular variant of papillary thyroid carcinoma. Am J Clin Pathol. 2002;118:602–603author reply 605–6
  30. Widder S, Guggisberg K, Khalil M, Pasieka JL. A pathologic re-review of follicular thyroid neoplasms: the impact of changing the threshold for the diagnosis of the follicular variant of papillary thyroid carcinoma. Surgery. 2008;144:80–85
  31. Chen KT, Rosai J. Follicular variant of thyroid papillary carcinoma: a clinicopathologic study of six cases. Am J Surg Pathol. 1977;1:123–130
  32. Chang HY, Lin JD, Chou SC, Chao TC, Hsueh C. Clinical presentations and outcomes of surgical treatment of follicular variant of the papillary thyroid carcinomas. Jpn J Clin Oncol. 2006;36:688–693
  33. Nair M, Kapila K, Karak AK, Verma K. Papillary carcinoma of the thyroid and its variants: a cytohistological correlation. Diagn Cytopathol. 2001;24:167–173
  34. Zidan J, Karen D, Stein M, Rosenblatt E, Basher W, Kuten A. Pure versus follicular variant of papillary thyroid carcinoma: clinical features, prognostic factors, treatment, and survival. Cancer. 2003;97:1181–1185
  35. Passler C, Prager G, Scheuba C, Niederle BE, Kaserer K, Zettinig G, et al. Follicular variant of papillary thyroid carcinoma: a long-term follow-up. Arch Surg. 2003;138:1362–1366
  36. Yuksel O, Kurukahvecioglu O, Ege B, Ekinci O, Aydin A, Poyraz A, et al. The relation between pure papillary and follicular variant in papillary thyroid carcinoma. Endocr Regul. 2008;42:29–33
  37. Liu J, Singh B, Tallini G, Carlson DL, Katabi N, Shaha A, et al. Follicular variant of papillary thyroid carcinoma: a clinicopathologic study of a problematic entity. Cancer. 2006;107:1255–1264

PII: S0039-6060(10)00040-1

doi: 10.1016/j.surg.2010.01.018

Surgery
Volume 148, Issue 3 , Pages 532-537 , September 2010