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Abstract
Supradiaphragmatic division of the vagus nerves has been performed in thirteen patients
with duodenal ulcer, in one patient with gastric ulcer, and in one with a gastrojejunal
ulcer. The patient with gastric ulcer has been apparently cured of his disease as
judged by the disappearance of symptoms and by x-ray and gastroscopic evidence. All
but one of the patients with duodenal ulcer have been greatly improved or cured, although
three patients have required gastroenterostomy because of persistence of obstructive
symptoms. The patient with the gastrojejunal ulcer, although improved, has been continued
on medical management. The excessive continuous night secretion of gastric juice has
been markedly reduced by the vagus section thus providing additional and perhaps conclusive
evidence that this abnormality is neurogenic in origin. The striking improvement in
these patients is in harmony with the view that gastroduodenal ulcer is a psychosomatic
disease, and that the central nervous system affects the stomach via the vagi, probably
chiefly through greatly augmenting the secretion of gastric juice.
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Article info
Publication history
Received:
October 16,
1944
Footnotes
☆Work aided by a grant from the Douglas Smith Foundation for Medical Research of the University of Chicago.
Identification
Copyright
© 1945 Published by Elsevier Inc.
