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In a series of 284 cases of gastric carcinoma, 243 (86 per cent) had achlorhydria or maximum acid values below 30 degrees, 220 cases (77 per cent) had achlorhydria or maximum acid values below 20 degrees, and 185 cases (65 per cent) had achlorhydria. Achlorhydria was uniformly present only in association with tumors of Borrmann Type I and these totaled but 3.2 per cent of the series. For tumors of Borrmann Types II, III, and IV, there was no constant association of either achlorhydria or hypochlorhydria. Twenty-eight per cent of the Type II tumors, 34 per cent of the Type III tumors, and 41 per cent of the Type IV tumors were associated with free acid on gastric analysis. In each of these groups the maximum acid values fell below 20 degrees in about one-third of the cases and exceeded 20 degrees in about two-thirds of the cases.
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Received: March 3, 1948
© 1948 Published by Elsevier Inc.