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Abstract
In a series of 284 cases of gastric carcinoma, 243 (86 per cent) had achlorhydria
or maximum acid values below 30 degrees, 220 cases (77 per cent) had achlorhydria
or maximum acid values below 20 degrees, and 185 cases (65 per cent) had achlorhydria.
Achlorhydria was uniformly present only in association with tumors of Borrmann Type
I and these totaled but 3.2 per cent of the series. For tumors of Borrmann Types II,
III, and IV, there was no constant association of either achlorhydria or hypochlorhydria.
Twenty-eight per cent of the Type II tumors, 34 per cent of the Type III tumors, and
41 per cent of the Type IV tumors were associated with free acid on gastric analysis.
In each of these groups the maximum acid values fell below 20 degrees in about one-third
of the cases and exceeded 20 degrees in about two-thirds of the cases.
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References
- Das Wachstum und die Verbreitungswege des Magencarcinoms.Mitt. a.d. Grenzgeb. d. Med. u. Chir. 1901; (Suppl.): 1-376
- Gastric Acidity Before and After the Development of Carcinoma of the Stomach.J. Nat. Cancer Inst. 1947; 7: 367-373
- Pathological Aspects of Carcinoma of the Stomach.in: Collected Papers of the Mayo Clinic and the Mayo Foundation. vol. 38. W. B. Saunders Company, Philadelphia1947: 19-24
- Chronic Gastritis, Its Relation to Gastric and Duodenal Ulcer and to Gastric Carcinoma.Am. J. Path. 1943; 19: 43-71
- The Pathology of Simple Gastritis.J. Path. & Bact. 1946; 58: 431
Article info
Publication history
Received:
March 3,
1948
Identification
Copyright
© 1948 Published by Elsevier Inc.
