Original communication| Volume 24, ISSUE 4, P695-702, October 1948

On the histology of surgically removed sympathetic ganglia

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      • 1.
        1. Ganglia removed by sympathectomy and stained by a variety of techniques have been compared to routine autopsy material, of known age and diagnosis.
      • 2.
        2. Abnormal findings in sympathetic ganglia of adults are exceedingly common and include: degenerating neurones, inflammatory infiltrations, increase of interstitial tissue, and hyalinized thickened walls of intrinsic veins.
      • 3.
        3. Ganglia of infants and children possess little connective tissue, delicate vascular walls, and few or no degenerate neurones.
      • 4.
        4. The most consistent pathologic findings are hyalinizod walls of intrinsic channels, usually venules, in most cases of essential hypertension and peripheral vascular disease. However, the incidence and intensity of these alterations are not strictly related to the severity of the disease nor to the age of the patient. Arterioles within the ganglia may present a normal appearance in cases of hypertension or peripheral vascular disease.
      • 5.
        5. The findings do not permit the establishment of a histologic Picture characteristic for either hypertension or peripheral vascular disease.
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