Original communication| Volume 31, ISSUE 5, P705-715, May 1952

Dermatofibrosarcoma protuberans

A review of the literature and presentation of three cases
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      • 1.
        1. The significant literature and the important clinical and pathological features of dermatofibrosarcoma protuberans are reviewed.
      • 2.
        2. The protuberant character of these lesions grossly is noted.
      • 3.
        3. This lesion may be considered to be intermediate in position between fibroma and sarcoma just as basal-cell epithelioma is intermediate in position between benign epithelial growths and squamous-cell carcinoma. Dermatofibrosarcoma protuberans also resembles basal-cell carcinoma in its tendency to recur locally and metastasize only very rarely.
      • 4.
        4. The treatment of choice is adequate, complete, surgical excision which should include several centimeters of surrounding normal tissue together with the fascia overlying the muscle deep to the lesion. In certain instances, the resultant wound may be extensive enough to require skin grafting.
      • 5.
        5. The accurate interpretation of the historical, physical, and histological findings is especially important when this lesion occurs on the extremities so that unnecessary radical amputations will be avoided.
      • 6.
        6. Three cases of dermatofibrosarcoma protuberans are presented.
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