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Abstract
Sixty-eight experiments have been performed in the course of developing an extracorporeal
heart pump mechanism for artificial maintenance of the circulation. Descriptions of
the pump mechanism, the methods of cannulation, and the techniques of replacing either
or both sides of the heart have been given.
The effect of pump activity on the organized elements of the blood has been studied.
Physiologic data on arterial blood pressure under varying conditions of pump activity
are discussed.
Pump replacement of cardiac function in these experiments has been performed using
the animal's own lung as the means of oxygenation of blood. The data are presented
concerning a series of 28 experiments with attempts at recovery of the animals after
a period of artificial maintenance of the circulation. Twenty-one (75 per cent) of
these animals recovered.
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References
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Article info
Publication history
Received:
August 22,
1951
Footnotes
☆This work has been aided by grants from the National Heart Institute of the United States Public Health Service, the Massachusetts Heart Association, and the Charlton Research Fund of Tufts College Medical School. It is a report of work in progress.
Identification
Copyright
© 1952 Published by Elsevier Inc.
