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- 1.1. Forty-two valid fresh venous autografts in growing pigs and thirty-six valid fresh venous autografts in mature dogs form the basis for this report. All of these grafts were implanted into the abdominal aortas of the animals.
- 2.2. Fresh venous autografts served as satisfactory conduits for blood, provided occlusion by thrombosis did not occur.
- 3.3. The factors of graft length and biterminal positive disproportion were highly significant in the development of early thrombosis.
- 4.4. Short-length fresh venous autografts with positive disproportion, negative disproportion, or made isodimensional by plication and implanted into the abdominal aorta of growing pigs had a high incidence of delayed thrombosis.
- 5.5. Autogenous vein grafts which remained patent had a tendency to dilate. This tendency was not related to the length of the grafts nor to the graft-aortic diameter ratio at the time of implantation.
- 6.6. Aneurysmal dilatations were found in a significant number of venous autografts in growing pigs which were found open six months after implantation. However, a lesser number of autoplastic vein grafts did not grow as rapidly as the host aorta.
- 7.7. Observations are being recorded on fresh venous autografts of the abdominal aorta in mature dogs implanted longer than thirty-three weeks.
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☆This work was aided in part by grants from the Division of Research Grants and Fellowships (Project H-1136), National Institutes of Health, Bethesda, Md., and Initiative 171 Research Funds provided by the State of Washington for research in the biological and medical sciences.
☆☆Read at the sixth annual meeting of the Society for Vascular Surgery, Chicago, Ill., June 8, 1952.
© 1953 Published by Elsevier Inc.