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Original communication Society for Vascular Surgery| Volume 33, ISSUE 2, P213-232, February 1953

A critical study of present criteria governing selection and use of blood vessel grafts

DOI:https://doi.org/10.5555/uri:pii:0039606053901081
A critical study of present criteria governing selection and use of blood vessel grafts
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      Abstract

      From many experiments on dogs since 1949 and from an analysis of 500 autopsies performed at Presbyterian Hospital in New York, certain facts have been derived concerning the procurement, storage, and use of aortic homografts.
      • 1.
        1. Satisfactory results have been obtained with nonviable grafts preserved by quick freezing or lyophilization or stored for over 40 days in a nutrient electrolyte solution.
      • 2.
        2. Viability of cells in a graft is not an essential factor in assuring functional success.
      • 3.
        3. The acceptable age of a donor individual should be estimated from his physiologic appearance and cause of death rather than from stated age.
      • 4.
        4. Individuals with a cause of death or associated condition which may be transmissible or about which the etiology is not fully understood should be excluded as donors at the present time.
      • 5.
        5. Emphasis should be directed toward rapid refrigeration of the body with less concern being exhibited over the interval of time between death and procurement of vessel grafts. Aseptic technique should still be employed when obtaining these vessels.
      • 6.
        6. Suitable donors, properly handled, should yield satisfactory grafts for a period well beyond 6 hours after death. Grafts obtained from 16 to 35 hours after death have been used clinically from the New York Vessel Bank with success.
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      Article info

      Footnotes

      ☆Aided by grants from the New York Heart Association and the American Heart Association.

      ☆☆Read at the sixth annual meeting of the Society for Vascular Surgery, Chicago, Ill., June 8, 1952.

      ★The opinions expressed in this paper are not necessarily those of the New York Vessel Bank Committee, but have played a part in the formulation of the present criteria governing the selection and use of preserved blood vessel grafts in this bank.

      Identification

      DOI: https://doi.org/10.5555/uri:pii:0039606053901081

      Copyright

      © 1953 Published by Elsevier Inc.

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