Original communication Society for Vascular Surgery| Volume 33, ISSUE 2, P213-232, February 1953

A critical study of present criteria governing selection and use of blood vessel grafts

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      From many experiments on dogs since 1949 and from an analysis of 500 autopsies performed at Presbyterian Hospital in New York, certain facts have been derived concerning the procurement, storage, and use of aortic homografts.
      • 1.
        1. Satisfactory results have been obtained with nonviable grafts preserved by quick freezing or lyophilization or stored for over 40 days in a nutrient electrolyte solution.
      • 2.
        2. Viability of cells in a graft is not an essential factor in assuring functional success.
      • 3.
        3. The acceptable age of a donor individual should be estimated from his physiologic appearance and cause of death rather than from stated age.
      • 4.
        4. Individuals with a cause of death or associated condition which may be transmissible or about which the etiology is not fully understood should be excluded as donors at the present time.
      • 5.
        5. Emphasis should be directed toward rapid refrigeration of the body with less concern being exhibited over the interval of time between death and procurement of vessel grafts. Aseptic technique should still be employed when obtaining these vessels.
      • 6.
        6. Suitable donors, properly handled, should yield satisfactory grafts for a period well beyond 6 hours after death. Grafts obtained from 16 to 35 hours after death have been used clinically from the New York Vessel Bank with success.
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