This paper is only available as a PDF. To read, Please Download here.
Abstract
Stimulation experiments in the monkey reveal dual hypothalamic influences increasing
the secretion of gastric hydrochloric acid.
The first originates in the anterior hypothalamus, is conducted through the vagus
nerve, and is blocked only by vagotomy. The peak of its response is prompt.
The second, whose peak response is later, arises in the posterior hypothalamus, is
conducted humorally through the pituitary-adrenal system, and is blocked only by adrenalectomy.
The increase in gastric hydrochloric acid induced by administration of insulin, exhibits
features of the responses to both anterior and posterior hypothalamic stimulation.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- The Relation of the Tuber Cinerium to Gastric and Cardiac Functions.J. Canad. M. A. 1932; 26: 278
- Digestion and Absorption in the Stomach.in: Harell's Textbook of Physiology. W. B. Saunders Company, Philadelphia1946: 1049
- Peptic Ulcers and the Interbrain.Surg. Gynec. & Obst. 1932; 55: 1
- Hypothalamic Control of the Anterior Pituitary Gland and Blood Lymphocytes.J. Physiol. 1950; 111: 335
- Chronic Stress and Peptic Ulcer. I. Effect of Corticotropin (ACTH) and Cortisone on Gastric Secretion.J. A. M. A. 1951; 147: 1529
- The Relationship of the Hypothalamus to Pituitary-Adrenocortical Function.in: Proc. First ACTH Conf. The Blakiston Company, Philadelphia1950: 134
- Ulceration of the Digestive Tract in the Dog Following Intracranial Procedures.Arch. Path. 1936; 21: 127
- Alterations in the Electrical Activity of the Hypothalamus Induced by Stress Stimuli.Am. J. Physiol. 1952; 169: 629
- A Manual of Pathological Anatomy. Vol. II. Blanchard & Lea, Philadelphia1855: 40 (Translated by Swaine, W. E.)
- The Effect of Lesions of the Hypothalamus Upon the Gastrointestinal Tract and Heart of Monkeys.Ann. Surg. 1935; 101: 363
Article info
Publication history
Received:
July 8,
1952
Footnotes
☆Aided by a grant from the National Institutes of Health, United States Public Health Service.
Identification
Copyright
© 1953 Published by Elsevier Inc.
