Original communication| Volume 37, ISSUE 4, P612-621, April 1955

Clinical observations on the use of dextran and modified fluid gelatin in combat casualties

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      Observations were made on the administration of 4,000 bottles of dextran to 2,000 casualties during the latter part of the Korean conflict. No toxic reactions were seen. A bleeding tendency following the administration of dextran, although not investigated, was not noted. This plasma volume expander proved to be most satisfactory. Many forward hospital surgeons felt that it was superior as an emergency solution to plasma or albumin.
      Patients who required 1,500 c.c. or less of resuscitative fluids could be satisfactorily restored with dextran alone. An acceptable ratio of dextran to blood was established for use when unlimited quantities of blood were not available.
      Observations were made on the administration of 200 units of modified fluid gelatin. The solution was nontoxic and did not gel. Although the molecular weight was low (average 34,000), the period of evacuation was only three and one-half hours and the circulation was supported for the required period.
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