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Abstract
Observations were made on the administration of 4,000 bottles of dextran to 2,000
casualties during the latter part of the Korean conflict. No toxic reactions were
seen. A bleeding tendency following the administration of dextran, although not investigated,
was not noted. This plasma volume expander proved to be most satisfactory. Many forward
hospital surgeons felt that it was superior as an emergency solution to plasma or
albumin.
Patients who required 1,500 c.c. or less of resuscitative fluids could be satisfactorily
restored with dextran alone. An acceptable ratio of dextran to blood was established
for use when unlimited quantities of blood were not available.
Observations were made on the administration of 200 units of modified fluid gelatin.
The solution was nontoxic and did not gel. Although the molecular weight was low (average
34,000), the period of evacuation was only three and one-half hours and the circulation
was supported for the required period.
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References
- Plasma Expanders.Surg., Gynec. & Obst. 1952; 95: 521
- Use of Dextran in Control of Shock Resulting From War Wounds.Arch. Surg. 1953; 66 (June): 730-740
- Plasma Retention and Urinary Excretion of Dextran and Modified Fluid Gelatin in Combat Casualties. A Study in Korea.Surgery. 1955; 37: 384
- The Use of Dextran and Gelatine as Plasma Volume Expanders in Combat Casualties.Final Report to the Army Medical Service Graduate School. July, 1954;
Howard, J. M., Frawley, J. P., Artz, C. P., and Sako, Y.: The Fate of Dextran and Modified Fluid Gelatine in Casualties With Post-traumatic Renal Insufficiency, Surg., Gynec. & Obst. In press.
Scott, R., Jr., and Howard, J. M.: Hepatic Function Following Wounding and Resuscitation With Plasma Expanders. Submitted for publication.
- Studies of Adrenal Function in Combat and Wounded Soldiers.Final Report to the Army Medical Service Graduate School. 1954;
- Evaluation of Plasma Substitutes in Clinical Shock: Dextran.in: Proc. Surg. Forum, Clin. Congress Am. Coll. Surgeons, 1951 W. B. Saunders Company, Philadelphia1952
Article info
Publication history
Received:
September 7,
1954
Identification
Copyright
© 1955 Published by Elsevier Inc.
