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Abstract
Endarterectomy has been performed in the femoral arteries of a group of animals with
experimental hypercholesterolemia and atherosclerosis. Nine of 14 vessels studied
in this manner were found ultimately to remain patent. Occluding thrombosis occurred
in five. Arteriography demonstrated some degree of luminal narrowing at the site of
endarterectomy in all arteries which remained patent and the extent could be correlated
with the degree of atherosclerosis observed at the time of operation. The findings
indicate that small atherosclerotic arteries often remain patent after experimental
endarterectomy, although reduction in the size of the lumen and development of thrombosis
are significantly greater in this group than in control animals without atherosclerosis.
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Article info
Publication history
Received:
April 28,
1960
Footnotes
☆Aided by Grant H-2864 from The National Heart Institute, National Institutes of Health, United States Public Health Service, Bethesda, Md.
Identification
Copyright
© 1960 Published by Elsevier Inc.