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Endarterectomy has been performed in the femoral arteries of a group of animals with experimental hypercholesterolemia and atherosclerosis. Nine of 14 vessels studied in this manner were found ultimately to remain patent. Occluding thrombosis occurred in five. Arteriography demonstrated some degree of luminal narrowing at the site of endarterectomy in all arteries which remained patent and the extent could be correlated with the degree of atherosclerosis observed at the time of operation. The findings indicate that small atherosclerotic arteries often remain patent after experimental endarterectomy, although reduction in the size of the lumen and development of thrombosis are significantly greater in this group than in control animals without atherosclerosis.
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Received: April 28, 1960
☆Aided by Grant H-2864 from The National Heart Institute, National Institutes of Health, United States Public Health Service, Bethesda, Md.
© 1960 Published by Elsevier Inc.