Advertisement
Surgery
Advanced searchSave search
Research Article| Volume 52, ISSUE 4, P660-663, October 1962

Download started.

Ok

Studies on hepatic blood flow and the rate of Bromsulphalein clearance in dogs with portacaval transposition

  • Thomas E. Starzl
    Footnotes
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • William A. Scanlon
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • William C. Shoemaker
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • Fred H. Thornton
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • Robert M. Wendel
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • Lawrence Schlachter
    Affiliations
    From the Departments of Surgery and Radiology, Northwestern University Medical School, Chicago, Ill., USA

    From the Department of Surgical Research of the Michael Reese Hospital and Medical Center, Chicago, Ill., USA

    From the Departments of Surgery, University of Colorado Denver, Colo., USA

    From the Denver Veterans Administration Hospital Denver, Colo., USA
    Search for articles by this author
  • Author Footnotes
    ∗ Markle Scholar. Present address: University of Colorado Medical School, Denver 20, Colo.
DOI:https://doi.org/10.5555/uri:pii:0039606062900740
Studies on hepatic blood flow and the rate of Bromsulphalein clearance in dogs with portacaval transposition
Previous ArticleA multiple catheter technique for studies or hepatic metabolism and blood flow in dogs with portacaval transposition
Next ArticlePortal hypertension in childhood
      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      Hepatic plasma and blood flows were determined in dogs with modified portacaval transposition. Mean hepatic blood flow was 43 ml. per kilogram per minute, approximately that expected in a normal dog. Similarly, the rate of Bromsulphalein clearance was in the range expected for normal dogs.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Register: Create an account
      Institutional Access: Sign in to ScienceDirect

      References

        • Blalock A.
        • Mason M.F.
        Observations on the blood flow and gaseous metabolism of the liver of unanesthetized dogs.
        Am. J. Physiol. 1936; 117: 328
        • Bradley S.E.
        • Ingelfinger F.J.
        • Bradley G.P.
        • Curry J.J.
        The estimation of hepatic blood flow in man.
        J. Clin. Invest. 1945; 24: 890
        • Child C.G.
        • Barr D.
        • Holswade G.R.
        • Harrison C.S.
        Liver regeneration following portacaval transposition in dogs.
        Ann. Surg. 1953; 138: 600
        • De Riemer R.H.
        • Hine D.E.
        • Harper H.A.
        An evaluation of ammonia intoxication in normal dogs and in dogs having a portacaval anastomosis.
        in: S. Forum. 5. 1954: 205
        • Drapanas T.
        • Kluge D.N.
        • Schenk W.G.
        Measurement of hepatic blood flow by Bromsulphalein and by the electromagnetic flowmeter.
        Surgery. 1960; 48: 1017
        • Heer F.W.
        • Silvius D.E.
        • Harper H.A.
        The relation between hepatic blood flow and function in normal dogs and dogs with cirrhosis after portacaval shunt or transposition.
        in: S. Forum. 9. 1960: 282
        • Lipscomb A.
        • Crandall Jr., L.A.
        Hepatic blood flow and glucose output in normal unanesthetized dogs.
        Am. J. Physiol. 1947; 148: 302
        • Meyer Jr., W.H.
        • Starzl T.E.
        The reverse portacaval shunt.
        Surgery. 1959; 45: 531
        • Owsley J.Q.
        • Goin J.M.
        • Clarke J.C.
        • Harper H.A.
        • McCorkle H.J.
        A comparison of galactose clearance by the liver following portacaval transposition or Eck fistula.
        in: S. Forum. 9. 1958: 515
        • Pratt E.B.
        • Benedict F.D.
        • Holmes J.H.
        Measurement of liver blood flow in unanesthetized dog using the Bromsulphalein dye method.
        Am. J. Physiol. 1952; 171: 471
        • Restrepo J.E.
        • Warren W.D.
        • Nolan S.P.
        • Muller W.H.
        Radioactive gold technique for the estimation of liver blood flow: Normal values and technical considerations.
        Surgery. 1960; 48: 748
        • Selkurt E.E.
        Comparison of the Bromsulphalein method with simultaneous direct hepatic blood flow.
        Circulation Res. 1954; 2: 155
        • Shoemaker W.C.
        Measurement of hepatic blood flow in the unanesthetized dog by a modified Bromsulphalein method.
        J. Appl. Physiol. 1960; 15: 473
        • Silen W.
        • Mawdsley D.L.
        • Weirich W.L.
        • Harper H.A.
        Studies of hepatic function in dogs with Eck fistula or portacaval transposition.
        A. M. A. Arch. Surg. 1957; 74: 964
        • Starzl T.E.
        • Butz Jr., G.W.
        • Munger D.H.
        Technique for portacaval transposition (addendum).
        J. S. Res. 1961; 1: 218
        • Starzl T.E.
        • Lazarus R.E.
        • Schlachter L.
        • Thornton F.H.
        • Wendel R.M.
        • Stearn B.
        • Scanlon W.A.
        A multiple catheter technique for studies of hepatic metabolism and blood flow in dogs with portacaval transposition.
        Surgery. 1962; 52: 654
        • Weiner A.Y.
        • Horwath S.M.
        Measurement of hepatic blood flow in the dog by the Bromsulphalein method.
        J. Clin. Invest. 1952; 31: 433

      Article info

      Publication history

      Received: February 15, 1962

      Footnotes

      ☆This work was supported by Grants A-3176, A-3115, and A-5489 from the United States Public Health Service, National Institutes of Health, Bethesda, Md.

      Identification

      DOI: https://doi.org/10.5555/uri:pii:0039606062900740

      Copyright

      © 1962 Published by Elsevier Inc.

      ScienceDirect

      Access this article on ScienceDirect

      The content on this site is intended for healthcare professionals.


      We use cookies to help provide and enhance our service and tailor content. To update your cookie settings, please visit the Cookie Preference Center for this site.
      Copyright © 2023 Elsevier Inc. except certain content provided by third parties.


      RELX