- 1.1. Oral cation exchange resin (Kayexalate) and sorbitol therapy have been shown to be effective in preventing a rise in systemic venous blood ammonia in dogs with Eck fistulas given blood by gastric tube.
- 2.2. Control studies using neomycin and magnesium citrate by tube were unsuccessful in preventing this rise in blood ammonia.
- 3.3. Orally administered Kayexalate and sorbitol are effective in significantly lowering blood ammonia levels in Eck-fistula dogs given an intravenous infusion of ammonium citrate, 2.0 per cent.
- 4.4. Clinical therapeutic experience with the oral cation exchange resin—sorbitol regimen was proposed.
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☆Supported in part by United States Public Health Service Grant (H-4260-C-2), United States Public Health Service Career Development Award AM-K3-13,702 and U.S. Army Contract DA-49-007-MD-1016.
☆☆Read at the Twenty-third Annual Meeting of the Society of University Surgeons, Cleveland, Ohio, Feb. 8–10, 1962.