Advertisement
Society of University Surgeons| Volume 52, ISSUE 1, P165-173, July 1962

Consideration of the fetus in surgery of the pregnant female

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      • 1.
        1. New techniques for in utero fetal studies have been used in the determination of the response of the fetal cardiovascular system to maternally administered Nembutal and epinephrine and maternal shock.
      • 2.
        2. Maternal infusion of Nembutal causes a significant deterioration in the fetal electrocardiogram prior to that of the mother.
      • 3.
        3. The fetus is sensitive to the direct injection of very small amounts of epinephrine.
      • 4.
        4. Administration of epinephrine to the pregnant animal decreases uterine artery blood flow and frequently lowers fetal arterial pressure.
      • 5.
        5. Epinephrine given directly to the fetus immediately after the injection of epinephrine into the mother often elevates fetal arterial pressure.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Adams F.H.
        • Assali N.
        • Cushman M.
        • Westersten A.
        Interrelationships of maternal and fetal circulations. I. Flow-pressure responses to vasoactive drugs in sheep.
        Pediatrics. 1961; 27: 627
        • Barcroft J.
        Researches on prenatal life.
        in: Basil Blackwell & Mott, Ltd.,, Oxford1946: 137
        • Becker R.F.
        • Flannagan E.
        • King J.E.
        The fate of offspring from mother receiving sodium pentobarbital before delivery.
        Neurology. 1958; 8: 776
        • Bieniarz J.
        • Reynolds S.R.M.
        Hemodynamic changes in the ewe affecting fetal heart rate in utero.
        Am. J. Physiol. 1960; 198: 128
        • Boucek C.M.
        • Renton A.D.
        Experimental studies of effect of Amytal upon the fetus and its transmission through the placenta of the white rat.
        Surg. Gynec. & Obst. 1931; 52: 841
        • Dille J.M.
        Studies on barbiturates; placental transmission of nonanesthetic doses of barbital.
        Am. J. Obst. & Gynec. 1936; 32: 328
        • Dornhorst A.C.
        • Young I.M.
        The action of adrenaline and noradrenaline on the placental and foetal circulations in the rabbit and guinea pig.
        J. Physiol. 1952; 118: 282
        • Elder Jr., J.D.
        • Nagano S.M.
        • Eastwood D.W.
        • Harnagel D.
        Circulatory changes associated with thiopental anesthesia in man.
        Anesthesiology. 1955; 16: 394
        • Flowers Jr., C.E.
        The placental transmission of barbiturates and thiobarbiturates and their pharmacological action on the mother and infant.
        Am. J. Obst. & Gynec. 1959; 78: 730
        • Faulconer A.
        • Patrick R.T.
        Hemodynamic effects of ether, cyclopropane or barbiturates.
        Ann. Rev. Med. 1957; 8: 349-360
        • Jackson B.T.
        • Clarke J.P.
        • Egdahl R.H.
        Direct lead fetal electrocardiography with undisturbed fetal maternal relationships.
        Surg. Gynec. & Obst. 1960; 110: 687
        • Jackson B.T.
        • Egdahl R.H.
        The performance of complex fetal operations in utero without amniotic fluid loss or other disturbances of fetal-maternal relationships.
        Surgery. 1960; 48: 564
        • Johnson S.R.
        The effect of some anaesthetic agents on the circulation in man.
        Acta chir. scandinav. (supp.). 1950–1951; 158: 143
        • Li T.H.
        • Reynolds R.N.
        • Rheinlander H.F.
        • Etsten B.E.
        Cardio-circulatory dynamics during thiopental anesthesia in human.
        in: ed. 2. Fed. Proc. 13. 1954: 380
        • Reynolds S.R.M.
        • Paul W.M.
        Circulatory responses of the fetal lamb in utero to increase of intrauterine pressure.
        Bull. John Hopkins Hosp. 1955; 97: 383