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Abstract
Data are presented showing an increase in histamine content of the breast afflicted
with chronic cystic mastitis as compared to normal.
Breast cyst fluid contains almost as much of the amine as human blood.
β-estradiol and progesterone have been found capable of histamine release from breast
at catalytic concentrations.
We suggest that those cyclic changes in the breast presenting as increase in size
and turgor are to a considerable extent the result of water imbibition due to the
permeability effects of histamine action.
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References
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Article info
Footnotes
☆Supported by United States Public Health Service Grant A-2926.
☆☆Read at the Twenty-third Annual Meeting of the Society of University Surgeons, Cleveland, Ohio, Feb. 8–10, 1962.
Identification
Copyright
© 1962 Published by Elsevier Inc.
