This paper is only available as a PDF. To read, Please Download here.
When measured physiological amounts of trypsin, trypsinogen, or chymotrypsin were injected into the obstructed gallbladder, acute cholecystitis resulted after 48 hours. Obstruction alone, intrinsic bacteria, and pH change did not appear to be significant etiological factors within the same period.
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- An evaluation of the common channel as a factor in pancreatic or biliary disease.Ann. Surg. 1960; 151: 379
- Studies relative to pathogenesis of cholecystitis, cholelithiasis, and pancreatitis.Ann. Surg. 1940; 112: 1005
- Acute cholecystitis associated with pancreatic reflux.Ann. Surg. 1936; 103: 67
- The role of trypsin and of bile salts in the pathogenesis of acute pancreatitis.in: ed. 2. S. Forum. 9. 1959: 533
- Crystalline soybean trypsin inhibitor.J. Gen. Physiol. 1947; 30: 391
- Effect of pancreatic secretions on the gallbladder.A. M. A. Arch. Surg. 1957; 74: 890
- National Formulary. American Pharmaceutical Association, Washington, D. C.,1961
- Pankreassaft in den Gallenwegen. Seine pathogenetische Bedeutung für die Entstehung der akuten Pankreserkrankungen.Arch. klin Chir. 1933; 175: 660
- The effect of pancreatic juice on the gallbladder.Surg. Gynec. & Obst. 1949; 89: 160
- An experimental study of the effect of pancreatic juice on the gallbladder.Gastroenterology. 1962; 42: 36
- The role of pancreatic juice in the production of gallbladder disease.Surg. Gynec. & Obst. 1931; 53: 433
- Pancreatic juice as a factor in the etiology of gallbladder disease.Surgery. 1937; 1: 928
- Further evidence that pancreatic juice reflux may be the etiological factor in gallbladder disease.Ann. Surg. 1939; 109: 187
☆Aided by a grant from the Comly-Coleman Fund of the College of Medicine. The Ohio State University, and by a Research Grant from the National Institutes of Health, Bethesda, Md.
☆☆Read at the Twenty-third Annual Meeting of the Society of University Surgeons, Cleveland, Ohio, Feb. 8–10, 1962.
© 1962 Published by Elsevier Inc.