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- 1.1. By the controlled injections of sterile polyethylene microspheres varying in size from 8 to 400 μ, all gradations of pancreatitis could be produced in dogs.
- 2.2. The severity of the lesion was inversely proportional to the size of the microsphere: the larger the microsphere, the less severe the lesion.
- 3.3. Hemorrhagic pancreatitis was produced in 11 hours in every instance with microspheres 8 to 20 μ in size.
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Received: August 14, 1961
☆Supported by a grant from the John A. Hartford Foundation and United States Public Health Service Grant A-1220.
© 1962 Published by Elsevier Inc.