Advertisement
Research Article| Volume 51, ISSUE 6, P786-792, June 1962

Download started.

Ok

Control of hemorrhage from the heart and aorta utilizing a plastic adhesive

      This paper is only available as a PDF. To read, Please Download here.

      Abstract

      A plastic adhesive methyl 2-cyanoacrylate (Eastman 910 Monomer) which polymerizes on pressure was used as a hemostatic agent in combination with a reinforcing muscle patch. It was found to be effective in the heparinized and nonheparinized animal and to provide a bond which remained secure at systolic blood pressure levels of 300 to 400 mm. Hg. No evidence of toxicity, excessive adhesion formation, or intravascular thrombosis was found when the plastic used was in the amounts required to control bleeding.
      It is felt that this adhesive should be a useful adjuvant as a hemostatic agent in the clinical situation where uncontrolled bleeding from major blood vessels is encountered during surgery.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Carton C.A.
        • Kessler L.A.
        • Seidenberg B.
        • Hurwitt E.S.
        A plastic adhesive method of small blood vessel surgery.
        World Neurol. 1960; 1: 356
        • Carton C.A.
        • Kessler L.A.
        • Seidenberg B.
        • Hurwitt E.S.
        Experimental studies in the surgery of small blood vessels. IV. Nonsuture anastomosis of arteries and veins using flanged ring prosthesis and plastic adhesive.
        S. Forum. 1961; 11: 238
        • Frantz V.K.
        • Clarke H.
        • Laltes R.
        Hemostatis with absorbable gauze (oxidized cellulose).
        Ann. Surg. 1944; 120: 181
        • Garrett H.E.
        • Law S.W.
        Control of vascular anastomotic hemorrhage in heparinized dogs with a rapidly polymerizing adhesive.
        S. Forum. 1961; 12: 254
        • Hardy R.W.
        • Nielson C.A.
        • Sherman R.T.
        • Leonard F.
        • Moncrief W.H.
        An acrylate amide foam arterial prosthesis.
        J. Thoracic Surg. 1959; 38: 652
        • Harvey S.C.
        Fibrin paper as an hemostatic agent.
        Ann. Surg. 1918; 68: 66
        • Light R.U.
        • Prentice H.R.
        Gelatin sponge.
        in: Surgical investigation of a new matrix used in conjunction with thrombin in hemostasis. ed. 2. Arch. Surg. 51. 1945: 69
        • Nathan H.S.
        • Nachlas M.M.
        • Solomon R.D.
        • Halpern B.D.
        • Seligman A.M.
        Nonsuture closure of arterial incisions using a rapidly polymerizing adhesive.
        Ann. Surg. 1960; 152: 648
        • Salvatore J.E.
        • Gilmer Jr., W.S.
        • Kashgarian M.
        • Barbee W.R.
        An experimental study of the influence of pore size of implanted polyurethane sponges upon subsequent tissue formation.
        Surg. Gynec. & Obst. 1961; 112: 463