Research Article| Volume 57, ISSUE 6, P839-845, June 1965

Myocardial function and contractile force affected by glucose loading of the heart during anoxia

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      In a series of 80 animal experiments, glucose loading of the heart afforded significant protection to the anoxic myocardium, as assessed by ventricular function curves and myocardial contractile-force studies. This myocardial protection was observed at 37 °, 28 °, and 10 °C. and was associated with markedly increased myocardial “glucose uptake.” An hypothesis to explain these findings is presented.
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