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Research Article| Volume 57, ISSUE 1, P131-138, January 1965

The limitations of heparin therapy after arterial reconstruction

DOI:https://doi.org/10.5555/uri:pii:0039606065901947
The limitations of heparin therapy after arterial reconstruction
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      Abstract

      The role of platelet thrombosis in occlusion of arteries is emphasized and contrasted with the importance of fibrin formation in veins. The feeble effect of heparin in protecting against thrombotic occlusion after arterial reconstruction is explained by the failure of the drug to inhibit the adhesiveness of blood platelets and its inability to block aggregation of platelets induced by adenosine diphosphate (ADP).
      The administration of heparin after arterial reconstruction is discouraged.
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      Article info

      Footnotes

      ☆Supported by grants from the Massachusetts Heart Association and the United States Public Health Service.

      ☆☆Presented at the Eighteenth Annual Meeting of the Society for Vascular Surgery, San Francisco, Calif., June 21, 1964.

      Identification

      DOI: https://doi.org/10.5555/uri:pii:0039606065901947

      Copyright

      © 1965 Published by Elsevier Inc.

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