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The effect of parasympathetic denervation of the abdominal viscera upon mesenteric blood flow was studied in 28 dogs. Total subdiaphragmatic vagotomy in 10 dogs resulted in an average reduction of 42 percent in blood flow through the common mesenteric vein. Division of the gastric branches alone resulted in no significant change in blood flow. Division of the celiac and hepatic branches caused a reduction in flow of 17 and 18 percent, respectively. There appears to be a relationship between previously observed atrophy of the small intestinal mucosa and decreased mesenteric blood flow following parasympathetic denervation in the dog.
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Received: August 17, 1964
☆This study has been supported in part by Grant AM 06685-02, National Institutes of Health.
© 1965 Published by Elsevier Inc.