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Abstract
Peptic ulcer in childhood is increasing in incidence and demonstrating an unsuspected
virulence. Surgery may thus play an increasing role in the therapy of this disease.
An experimental study of the effects of the major operations for peptic ulcer on the
growth and nutrition of puppies was carried out. Vagotomy and pyloroplasty did not
alter the development of the animals as compared with the control group. Following
vagotomy and antrectomy or subtotal gastrectomy there was an immediate loss of weight
with a subsequent growth lag and deficit for the entire period of observation. Hematologic,
roentgenologic, and fat-absorption studies were normal in all groups. On the basis
of this study the authors feel that vagotomy and pyloroplasty will least disturb growth
and nutrition in the young, and if this procedure is effective in controlling the
ulcer diathesis, it should be the operation of choice in children.
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Article info
Publication history
Received:
March 31,
1964
Identification
Copyright
© 1965 Published by Elsevier Inc.
