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Research Article| Volume 57, ISSUE 2, P285-290, February 1965

Stimulation of gastric secretion by hypercarbia

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      Abstract

      The effect of hypercarbia on gastric secretion in the unanesthetized dog has been studied using Heidenhain, Pavlov, and total gastric pouchs. The results of these experiments suggest that the vagus nerve is necessary to obtain increased gastric secretion during acute respiratory acidosis.
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      References

        • Apperley F.L.
        Gastric acidity and its significance. A clinical and experimental study.
        Lancet. 1936; 1: 5
        • Apperley F.L.
        • Crabtree M.G.
        The relationship of gastric secretion to the chemical composition of the blood.
        J. Physiol. 1931; 73: 331
        • Blakemore W.S.
        • Wolffson S.K.
        Respiratory insufficiency as a factor in postoperative gastrointestinal bleeding.
        J. Thoracic & Cardiovas. Surg. 1962; 44: 494
        • Browne J.S.L.
        • Vineburg A.M.
        Interdependence of gastric secretion and CO2 content of blood.
        J. Physiol. 1932; 75: 345
        • Campbell G.S.
        • Haddy F.J.
        • Brown Jr., E.B.
        Effect of pH changes on vagal inhibition of the heart.
        in: S. Forum. 5. 1953: 283
        • Davenport W.H.
        Gastric carbonic anhydrase in dogs.
        Am. J. Physiol. 1940; 128: 725
        • Eiseman B.
        Respiratory insufficiency as a factor in postoperative gastrointestinal bleeding.
        J. Thoracic & Cardiovas. Surg. 1962; 44 (Discussion): 494
        • Fatev D.S.
        Gastric secretion after bronchopulmonary block, Vaproez.
        Lekoklinoserderchnok Patol. 1961; 2: 64
        • Fatev D.S.
        Gastroenterology. 1961; 42 (Abstracted in): 665
        • Gray J.S.
        • Bradley W.B.
        • Ivy A.C.
        On the preparation and biological assay of enterogastrone.
        Am. J. Physiol. 1937; 118: 463
        • Greene A.
        • Dundee J.
        The association of chronic pulmonary emphysema and chronic peptic ulceration.
        Canad. M. A. J. 1952; 67: 438
        • Jemerin E.E.
        • Hollender F.
        • Weinstein V.
        Comparison of insulin and food as stimuli of vagal and non-vagal gastric pouches.
        Gastroenterology. 1943; 1: 500
        • Latts E.M.
        • Cummins J.F.
        • Zieve L.
        Peptic ulcer and pulmonary emphysema in the hospitalized patient.
        A. M. A. Arch. Int. Med. 1956; 97: 576
        • Lowell F.C.
        • Franklin W.
        • Michelson A.C.
        • Schiller I.W.
        A note on the association of emphysema, peptic ulcer, and smoking.
        New England J. Med. 1956; 234: 123
        • Plotkin Z.
        The syndrome of gastroduodenal disease associated with chronic cor pulmonale.
        Dis. Chest. 1957; 31: 195
        • Richards J.B.
        • Stein S.N.
        The effect of CO2 exposure and respiratory acidosis on adrenal 17 hydroxy corticosteroid secretion in anesthetized dogs.
        Am. J. Physiol. 1957; 188: 1
        • Ridgen B.G.
        Chest disease and peptic ulcer.
        Gut. 1961; 2: 89
        • Silen W.
        • Brown W.H.
        • Eisman B.
        Peptic ulcer and pulmonary emphysema.
        A. M. A. Arch. Surg. 1959; 78: 897
        • Tenney S.M.
        The effect of CO2 on neurohumoral and endocrine mechanisms.
        Anesthesiology. 1960; 21: 614
        • Tenney S.M.
        • Naitove A.
        Effects of alveolar oxygen and carbon dioxide on gastric secretion.
        in: ed. 2. Fed. Proc. 19. 1960: 190
        • Trask C.
        • Cree E.
        Oximeter studies on patients with chronic obstructive emphysema, awake and during sleep.
        New England J. Med. 1962; 266: 639
        • Weber J.M.
        • Gregg L.A.
        The coincidence of benign gastric ulcer and chronic pulmonary disease.
        Ann. Int. Med. 1953; 42: 1026
        • Zukosi C.
        • Lee H.
        • Hume D.
        The effect of hypothalamic stimulation on gastric secretion and adrenal function in the dog.
        in: ed. 2. S. Forum. 12. 1961: 286