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Abstract
Histologic examination was performed upon 8 autologous arterial patch grafts inserted
into the circumflex coronary artery for 3 to 18 months. All arteries remained patent
for 6 months, though 2 of the 8 occluded between 6 and 15 months. The histologic sections
showed moderate fibrosis replacing 40 to 50 percent of the arterial wall, but the
integrity of the arterial wall was well preserved. Smooth muscle cells were present
in the media with a frequency estimated at 30 percent of normal.
Venous patch grafts have been reported to undergo extensive fibrosis within 60 days
after insertion, being converted to principally fibrous tissue. Since experimental
data indicates that details of technique greatly influence the patency rate following
reconstruction of 3 to 4 mm. arteries, it would seem preferable to employ an autologous
arterial patch graft for reconstruction whenever patch grafting is used in such small
arteries.
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References
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Article info
Publication history
Received:
July 13,
1964
Footnotes
☆Supported by United States Public Health Service Grant H-6850 and the Fred Rankin Surgical Fund.
Identification
Copyright
© 1965 Published by Elsevier Inc.
