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Original communication| Volume 69, ISSUE 2, P251-255, February 1971

Adrenal injury during repair of diaphragmatic hernia in infants

  • Richard C.M. Cook
    Footnotes
    Affiliations
    From the Departments of Surgery and Pathology, The Children's Orthopedic Hospital and Medical Center, Seattle, Wash., USA

    From the Departments of Surgery and Pathology, University of Washington School of Medicine Seattle, Wash., USA
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  • J.Bruce Beckwith
    Affiliations
    From the Departments of Surgery and Pathology, The Children's Orthopedic Hospital and Medical Center, Seattle, Wash., USA

    From the Departments of Surgery and Pathology, University of Washington School of Medicine Seattle, Wash., USA
    Search for articles by this author
  • Author Footnotes
    ∗ Present address: Alder Hey Children's Hospital, Liverpool 12, England.
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      Abstract

      The mortality from diaphragmatic hernia remains high; at times the exact mode of death has not been readily apparent from the clinical course or the autopsy findings.
      Fifteen out of 17 cases of diaphragmatic hernia who came to autopsy after operation at this hospital were found to have extensive adrenal hemorrhage. It is suggested that the adrenal damage may have caused enough insufficiency to contribute to these deaths; we consider this sufficient evidence to advocate great care while working in the region of the adrenal glands in the newborn child, and to consider the possibility of a relative adrenal insufficiency in the infant whose postoperative progress following repair of a diaphragmatic hernia is poor.
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