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Thirteen baboons were subjected to hypothermic and asanguineous total body perfusion and to replacement with packed, human, red blood cells. In effect, this was a rapid plasmapheresis of approximately 90 percent of the blood volume. Plasma protein refill progressed rapidly with replacement of up to 49 percent in one hour. The protein flow via the thoracic duct was inadequate to account for this rapid refill.
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Accepted: March 13, 1970
☆The funds for this study were provided by United States Air Force Project 7756.
© 1971 Published by Elsevier Inc.