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A family is described in which four members in three successive generations developed Wilms' tumor of kidney. The parent and offspring were thus affected. The diagnosis was confirmed by histological examination in three of them. In three patients, the right kidney was the one involved, and in one instance with bilateral tumors, the right kidney tumor developed first. The average age at development of tumor has been younger than the average for sporadic tumors. Possible etiologic role of heredity is suggested.
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Accepted: April 3, 1972
© 1972 Published by Elsevier Inc.