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Original communication| Volume 75, ISSUE 2, P213-219, February 1974

Successful reversal of lethal carbon monoxide intoxication by total body asanguineous hypothermic perfusion

  • Juan C. Agostini
    Affiliations
    From the Departments of Surgery of the Washington Hospital Center, The George Washington University Washington, D. C., USA

    From the George Hyman Research Foundation Washington, D. C., USA

    From the Department of Toxicology of the Armed Forces Institute of Pathology, Washington, D. C., USA
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  • Ruben G. Ramirez
    Affiliations
    From the Departments of Surgery of the Washington Hospital Center, The George Washington University Washington, D. C., USA

    From the George Hyman Research Foundation Washington, D. C., USA

    From the Department of Toxicology of the Armed Forces Institute of Pathology, Washington, D. C., USA
    Search for articles by this author
  • Solomon N. Albert
    Affiliations
    From the Departments of Surgery of the Washington Hospital Center, The George Washington University Washington, D. C., USA

    From the George Hyman Research Foundation Washington, D. C., USA

    From the Department of Toxicology of the Armed Forces Institute of Pathology, Washington, D. C., USA
    Search for articles by this author
  • Leo R. Goldbaum
    Affiliations
    From the Departments of Surgery of the Washington Hospital Center, The George Washington University Washington, D. C., USA

    From the George Hyman Research Foundation Washington, D. C., USA

    From the Department of Toxicology of the Armed Forces Institute of Pathology, Washington, D. C., USA
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  • Karel B. Absolon
    Affiliations
    From the Departments of Surgery of the Washington Hospital Center, The George Washington University Washington, D. C., USA

    From the George Hyman Research Foundation Washington, D. C., USA

    From the Department of Toxicology of the Armed Forces Institute of Pathology, Washington, D. C., USA
    Search for articles by this author
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      Abstract

      Total body asanguineous hypothermic perfusion proved successful as a treatment of otherwise acute lethal carbon monoxide intoxication in dogs. The technique may prove the therapy of choice in human carbon monoxide poisoning. The rapidity with which carboxyhemoglobin can be removed and replaced with normal hemoglobin containing red blood cells and the technical safety of the procedure warrants its clinical exploration in suitable cases.
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