This paper is only available as a PDF. To read, Please Download here.
Abstract
After administration of high systemic doses of heparin verified by assay, common carotid
arteries in the rat were divided and sutured. Scanning electron microscope observations
of endothelial surfaces showed a decrease in platelet adhesion, as well as a reduction
in the adherence of other circulatory blood elements when compared to controls. This
is the first report indicating the in vivo effect of high dose systemic heparin on
platelets.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
References
- Scanning electron microscopic observations of the common carotid artery endothelium in the rat. II. Sutured arteries.Surg. Neurol. 1975; 4: 258
- Inhibited platelet adhesion: A nonthrombogenic characteristic of a heparin coated surface.Surgery. 1974; 75: 643
- A method for the measurement of platelet adhesiveness by use of dialysis membranes in a test cell.Br. J. Haematol. 1973; 24: 377
Article info
Publication history
Accepted:
November 3,
1975
Identification
Copyright
© 1976 Published by Elsevier Inc.
