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Original communication| Volume 81, ISSUE 4, P376-381, April 1977

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The pulse-reappearance time: An index of over-all blood flow impairment in the ischemic extremity

  • Arnost Fronek
    Correspondence
    Reprint requests: A. Fronek, M.D., Ph.D., AMES-Bioengineering, School of Medicine, M-005, Basic Science Building, Room 5028, University of California, San Diego, La Jolla, Calif. 92093.
    Affiliations
    From the Departments of AMES-Bioengineering, Radiology and Surgery, School of Medicine, University of California, San Diego, La Jalla, Calif., USA
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  • Marc Coel
    Affiliations
    From the Departments of AMES-Bioengineering, Radiology and Surgery, School of Medicine, University of California, San Diego, La Jalla, Calif., USA
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  • Eugene F. Bernstein
    Affiliations
    From the Departments of AMES-Bioengineering, Radiology and Surgery, School of Medicine, University of California, San Diego, La Jalla, Calif., USA
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      Abstract

      A simple test is described to evaluate limb blood supply. The technique utilizes the delayed reappearance of the volume pulse after transient arterial occlusion. As monitored from the toe by a mercury-in-rubber gauge, pulse reappearance (PRT) was instantaneous (less than one second) and the 50 percent of control amplitude reappearance time (PRT/2) was 3.4 ± 0.8 seconds in 22 control subjects. A significant delay of the PRT and especially of PRT/2 was found in 60 patients with angiographically documented ischemic disease of the lower extremities. The delay was correlated closely with the severity of the disease: the mean PRT/2 for single level arterial disease (aortoiliac, femoropopliteal, posterior tibial, or anterior tibial artery obstruction) was approximately 25 seconds, and the mean PRT/2 associated with multilevel occlusion was 71 seconds. Since the technique is very simple, it may be used as a quick screening and follow-up procedure to detect the presence and over-all severity of peripheral arterial occlusive disease.
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