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Abstract
A prospective study of 72 limbs treated with phenol sympatholysis for inoperable peripheral
arterial occlusive disease was carried out in order to determine which factor or combination
of factors could most accurately be used to predict the success or the failure of
the sympathetic interruption. Seven variables were recorded prior to phenol sympatholysis
and the patients were followed up to 3 years in order to determine the degree of success
or failure of the sympathectomy. The results of discriminant function analysis of
these data showed that the most important variables in predicting the outcome were
(1) the level of ankle systolic pressure, (2) the presence or absence of a neuropathy,
and (3) the extent of the ischemic damage. The correct outcome was predicted in 87%
of the cases. Using these three variables, multiple regression analysis was performed
to construct a table showing the percentage chance of a successful outcome from a
sympathectomy. The results show that a phenol sympathectomy is likely to be successful
in the management of a patient with peripheral arterial occlusive disease if there
is no evidence of a somatic (and hence autonomic) neuropathy, if the ankle systolic
pressure is above 30 mm Hg, and if the tissue damage is not too extensive (i.e., only
rest pain, night pain, or digital gangrene is present).
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Article info
Publication history
Accepted:
May 25,
1979
Footnotes
☆Supported by grants from the Medical Research Council of Canada and the Ontario Heart Foundation.
Identification
Copyright
© 1980 Published by Elsevier Inc.
