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Abstract
A single-blind, randomized clinical trial of 56 female subjects was conducted to determine
whether decreased consumption of caffeine decreases breast pain/tenderness or nodularity
in patients with suspected benign proliferative breast disease. The subjects were
randomly assigned to one of three groups—a control group (no dietary restrictions),
a placebo group (cholesterol-free diet), and an experimental group (caffeine-free
diet). At the initial examination, the subjects reported on the presence of breast
pain, the degree to which pain affects daily activities, the frequency of pain, the
degree of pain associated with breast examinations, and the degree of pain associated
with close-fitting clothing. Subjects were then examined and the four quadrants of
each breast were rated on a scale of 0 to 3 (0 = normal, fatty tissue, 1 = little
seedy bumps or fine nodularity, 2 = discrete nodules or ropy tissue, 3 = confluent
areas, hard or soft masses). Subjects in all three groups returned for 2- and 4-month
follow-up examinations. Total nodularity scores, degree of pain/tenderness, and compliance
with dietary restrictions were analyzed. The data showed that decreased caffeine consumption
did not result in a significant reduction of palpable breast nodules or in a lessening
of breast pain/tenderness.
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Article info
Publication history
Accepted:
November 25,
1986
Footnotes
☆Supported by a grant from the Family Health Foundation.
Identification
Copyright
© 1987 Published by Elsevier Inc.
