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Original communication| Volume 109, ISSUE 5, P633-639, May 1991

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Assessment of aortoiliac obstructive disease by Doppler spectrum analysis of blood flow velocities in the common femoral artery at rest and during reactive hyperemia

  • W.N.J.C. van Asten
    Correspondence
    Reprint requests: W. N. J. C. van Asten, PhD, Clinical Vascular Laboratory, St. Radboud University Hospital, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
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  • W.J. Beijneveld
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
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  • B.R. Pieters
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
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  • H.J.J. van Lier
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
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  • P.F.F. Wijn
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
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  • S.H. Skotnicki
    Affiliations
    Clinical Vascular Laboratory, Department of Cardiothoracic Surgery, St. Radboud University Hospital, Nijmegen, The Netherlands

    Department of Medical Statistics, University of Nijmegen, Nijmegen, The Netherlands
    Search for articles by this author
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      Abstract

      Aortoiliac obstructive disease was assessed by Doppler spectrum analysis of blood flow velocities in the common femoral artery measured both at rest and during reactive hyperemia. The intraarterial femoral artery pressure measured at rest and during reactive hyperemia served as the “gold standard” for the definition of a hemodynamically significant aortoiliac stenosis. Our results, obtained from 93 patients (136 limbs), showed that differences between Doppler spectra obtained from limbs with a hemodynamically significant aortoiliac stenosis and those from limbs without were more pronounced during reactive hyperemia than at rest. The best assessment of aortoiliac obstructive disease could be obtained with a combination of parameters derived from Doppler spectra measured at rest and during reactive hyperemia. With these parameters, obtained by multivariate analysis, 85% of the limbs were diagnosed correctly compared with the gold standard. If angiographic data were added to the gold standard, even 91% of the limbs were diagnosed correctly. We conclude that analysis of Doppler spectra obtained noninvasively from the common femoral artery at rest and during reactive hyperemia provides an accurate hemodynamic assessment of the aortoiliac segment.
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