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Background. Thirty-two patients who were 70 years of age or older underwent hepatic resection in the treatment of hepatocellular carcinoma. There were 25 men and 7 women. Age ranged from 70 to 84 years, averaging 74 ± 3 years (mean ± SD). Underlying liver diseases were associated in all patients but one, cirrhosis of the liver in 22, and chronic hepatitis in nine.
Methods and Results. The operative mortality rate within 1 month was 12.5%, and the overall in-hospital death rate was 18.8%. The 5-year survival rate was 17.6% for all patients and 24.3% when six hospital deaths were excluded. The Child's grade was a good predictor for early and late morbidity and death, the 5-year survival rate of patients with Child's class A disease being 30%. Retrospective comparisons were conducted between the current patients and patients younger than 50 years old who had been operated on during the same period: resectability rate, 61.5% versus 57.8%; hospital mortality rate, 18.8% versus 11.6%; and 5-year survival rate, 24.3% versus 48.6%, respectively.
Conclusions. These results seem to indicate that the treatment policy of hepatocellular carcinoma in the aged should be identical to that in young people.
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- Aging and the liver.in: 2nd ed. Progress in liver diseases. vol 8. Grune & Stratton, New York1985: 659-683
- Operative risk factors of colon resection in the elderly.Ann Surg. 1980; 192: 743-746
- Mortality and gastrointestinal surgery in the aged.Arch Surg. 1981; 116: 788-791
- Influence of age on mortality of colon surgery.Am J Surg. 1985; 150: 65-70
- Biliary tract surgery and cirrhosis: a critical combination.Surgery. 1981; 90: 577-583
- Cholecystectomy in cirrhotic patients: a formidable operation.Am J Surg. 1982; 143: 55-60
- Predictors of surgical mortality in patients with cirrhosis and nonvariceal gastroduodenal bleeding.Surg Gynecol Obstet. 1974; 139: 65-68
- Morbidity and mortality after operation in nonbleeding cirrhotic patients.Am J Surg. 1983; 146: 306-309
- Clarification of risk factors for abdominal operations in patients with hepatic cirrhosis.Ann Surg. 1984; 199: 648-655
- Evaluation of hepatic resection for hepatocellular carcinoma in the elderly.Br J Surg. 1987; 74: 471-473
- Hepatic resection for hepatocellular carcinoma elderly patients.Am J Surg. 1988; 155: 238-241
- Hepatic resection in the elderly.Ann Surg. 1990; 211: 141-145
- Le Foie: etudes anatomiques et chirurgicales.Masson, New York1957
- Prediction of variceal hemorrhage in cirrhosis: a prospective follow-up study.Gastroenterology. 1991; 100: 1332-1337
- Factors affecting the morbidity of elective liver resection.Am J Surg. 1987; 153: 189-196
Accepted: October 6, 1991
© 1993 Published by Elsevier Inc.