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Abstract
Background. The role of hepatic resection for noncolorectal gastrointestinal malignancies involving
the liver is not well defined. To address this issue we studied our experience with
resection of liver tumors arising from primary gastric malignancies.
Methods. A retrospective study of 195 patients who underwent a total of 207 liver resections
identified 12 patients with primary gastric cancer who underwent 16 resections for
liver involvement. There were 10 adenocarcinomas and two leiomyosarcomas. We examined
the type of hepatic surgery, the status of residual disease, and the primary histologic
findings. Morbidity, mortality, and actual survival rates were recorded.
Results. Thirty-day operative mortality was 8.3% (1 of 12). Hospital mortality was 25% (3
of 12). Operative morbidity occurred in three of nine survivors (33%). Synchronous
en bloc resection (n = 3) of stomach and liver for adenocarcinoma produced two long-term
survivors (no evidence of disease for 10 and 13 years). Mean survival after synchronous
discontinuous resection (n = 4) was 8 months (range, 2 to 17 months). Metachronous
resection for adenocarcinoma (n = 3) produced one long-term survivor (74 months),
and one patient with recurrent leiomyosarcoma underwent a total of five liver resections
and survived 64 months.
Conclusions. For adenocarcinoma, en bloc resection of contiguous liver involvement produced long-term
survivors. Synchronous resection of discontinuous metastases did not. Metachronous
resection of isolated disease and multiple resections of recurrent isolated disease
may have value in carefully selected patients.
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Article info
Footnotes
☆Presented at the Fiftieth Annual Meeting of the Central Surgical Association, Cincinnati, Ohio, March 4–6, 1993.
Identification
Copyright
© 1993 Published by Elsevier Inc.
