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Abstract
Background. Computed tomography and endoscopic drainage are used increasingly to treat pancreatic
pseudocysts (PP). We reviewed our experience with PP to compare the outcomes of patients
operated on initially (group 1) with those whose nonoperative treatment failed (computed
tomography-guided or endoscopic drainage) before operation (group 2).
Methods. The records of 70 consecutive patients operated on for PP were reviewed. The 52 patients
(74%) in group 1 and 18 (26%) in group 2 were compared in terms of clinical features,
laboratory lest results on examination and before operation, operative findings, morbidity,
mortality, and recurrence rates.
Results. Before the initial drainage attempt, mean serum amylase level was higher in group
2 (542 ± 25 vs 163 ± 17 IU/L; p = 0.01). All other laboratory values were similar.
Before operative drainage, group 2 patients had lower hemoglobin (10.7 ± 0.5 vs 12.2
± 0.3 gm/dl; p < 0.05) and serum albumin level (2.7 ± 0.2 vs 3.5 ±0.1 mg/dl; p < 0.01)
than group 1. Morbidity was twice as frequent in group 2 (33% vs 14%). The time from
initial attempt at drainage to PP resolution was longer in group 2 (104 ± 36 vs 20
± 4 days; p = 0.01). However, the time from operation to resolution was similar in
both groups (21 ± 8 vs 20 + 4 days).
Conclusions. Failed nonoperative drainage is associated with a protracted illness and carries
a risk of increased morbidity after operative intervention.
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Article info
Footnotes
☆Presented at the Fiftieth Annual Meeting of the Central Surgical Association, Cincinnati, Ohio, March 4–6, 1993.
Identification
Copyright
© 1993 Published by Elsevier Inc.