This paper is only available as a PDF. To read, Please Download here.
Abstract
Between 1982 and 1991, 20 patients of median age 44 (range 22–76) years were treated
for non-functioning neuroendocrine tumours of the pancreas. Presenting features were
obstructive jaundice (seven patients), abdominal pain (seven), weight loss (six),
abdominal mass (eight) and severe haemorrhage (four). Gut hormone profiles were normal
except for one patient who had a raised pancreatic polypeptide level. Contrast-enhanced
computed tomography localized the tumour in 17 patients and visceral angiography in
14 of 15; all but three tumours were highly vascular. Ten patients underwent curative
resection, and the remainder were managed palliatively by resection (four), bypass
procedures (three) or biopsy alone (three). There were two postoperative deaths and
seven early complications. Seven of the remaining 18 patients have died from disease
a median of 16 (range 4–30) months after presentation. The 11 survivors, eight of
whom had curative resections, have been followed for a median of 42 (range 7–72) months.
Ten patients are asymptomatic but only five are free from disease. These tumours are
seldom curable by radical surgery, but patients may remain free from symptoms for
many years.
To read this article in full you will need to make a payment
Purchase one-time access:
Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online accessOne-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:
Subscribe to SurgeryAlready a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
Article info
Identification
Copyright
© 1993 Published by Elsevier Inc.
