Background. Bilateral synchronous breast cancer is uncommon (accounting for 1.0%-2.6% of all patients with breast cancer), and most physicians do not accumulate a large personal experience of patients with this disease. We reviewed our experience with patients with bilateral synchronous breast cancer, focusing on the mode of detection and histologic features in the 2 breasts. Methods. The charts of patients who were treated at this institution for bilateral synchronous breast cancer during the 15-year period of 1984 through 1999 were reviewed. Information regarding age, mode of detection, histopathologic features, treatment, and overall survival were analyzed. Results. During the study period, 51 patients (all women) were treated at our institution for bilateral synchronous breast cancer. This comprised 2.1% of all patients (n = 2382 patients) treated for breast cancer during the same period of time. The first cancer was detected by palpation in 81% and by mammography in 14%. The corresponding figures for the contralateral cancer were 24% and 54%, respectively. The histologic type of cancer was identical in the 2 breasts in 29 patients (57%) and was different between the 2 breasts in 22 patients (43%). The overall 10-year survival rate was 63%. Conclusions. Bilateral synchronous breast cancer is often detected by mammography and is frequently of the same histologic type as the index cancer. A better awareness of the risk for this disease may help detect bilateral breast cancer earlier. (Surgery 2000;128:702-7.)
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- Bilateral primary breast cancer: a prospective study of disease incidence.Br J Surg. 1984; 71: 711-714
- Bilateral cancer of the breast: a review of clinical, histologic, and immunohistologic characteristics.Surgery. 1991; 110: 617-622
- Risk factors predicting the incidence of second primary breast cancer among women diagnosed with a first primary breast cancer.Am J Epidemiol. 1992; 136: 925-936
- Bilateral breast cancer.Am Surg. 1993; 59: 733-735
- Bilateral carcinoma of the breast.Eur J Surg Oncol. 1993; 19: 259-264
- Occurrence and prognosis of contralateral carcinoma of the breast.J Am Coll Surg. 1994; 178: 390-396
- Breast conservation therapy for stage I-II synchronous bilateral breast carcinoma.Cancer. 1997; 79: 1362-1369
- Bilaterality and recurrence for lobular breast cancer: considerations for treatment.Ann Surg Oncol. 1997; 4: 198-202
- Survival in bilateral breast cancer.Cancer. 1993; 71: 172-176
- Primary synchronous bilateral breast cancer: epidemiological approach.Breast Cancer Res Treat. 1988; 12: 311-314
- Evolving perspectives in contralateral breast cancer.Eur J Cancer. 1998; 34: 2000-2009
- Survival in bilateral breast cancer.Cancer. 1985; 55: 1414-1421
- Factors influencing survival in bilateral breast cancer.J Surg Oncol. 1981; 16: 3433-3448
- Experience with opposite breast biopsy in patients with operable breast cancer.Cancer. 1976; 37: 43-45
- Synchronous, bilateral mastectomy.J Surg Oncol. 1995; 59: 75-79
- Current controversies in breast cancer management.Curr Probl Surg. 1999; 36: 163-216
- Feasibility of breast conservation therapy in metachronous or synchronous breast cancer.Ann Surg Oncol. 1999; 6: 102-108
- Pathologic findings from the National Surgical Adjuvant Breast Project.Cancer. 1984; 54 (Protocol No. 4): 3002-3011
- SEER cancer statistics review, 1973-1997. National Cancer Institute, Bethesda (MD)2000
*Reprint requests: Per-Olof Hasselgren, MD, Department of Surgery, University of Cincinnati, 231 Bethesda Avenue, ML 558, Cincinnati, OH 45267-0558.
© 2000 Mosby, Inc. Published by Elsevier Inc. All rights reserved.