Abstract
Background: Peritonitis is, even today, a significant source of death and complications. The
objective of this study was to determine the morbidity and mortality rates, the incidence
of reoperations, and the need for additional treatment strategies (on demand) in patients
with diffuse peritonitis. Methods: Prospective analysis including all patients (n = 258) with diffuse peritonitis admitted
to our surgical service between November 1993 and April 1998 who underwent a uniform
surgical treatment concept of peritonitis including early intervention, source control,
and extensive intraoperative lavage. Results: The 258 patients with diffuse peritonitis averaged a mean Mannheim Peritonitis Index
of 27.1 points (range, 11-43 points). Source control at the initial operation was
possible in 230 of the patients (89%), of those, 21 patients (9%) needed reintervention.
In 28 patients (11%), source control was not possible at the initial operation. Twenty
of these patients (71%) had to undergo additional treatment strategies (on demand)
such as continuous lavage and/or laparostomy. Overall 228 of the 258 patients (88%)
needed just 1 initial surgical intervention. The overall morbidity rate was 41%; the
rate of reoperation was 12%, and the hospital mortality rate was 14%. Conclusions: A conservative surgical treatment concept supplemented with “extensive” intraoperative
lavage reduces the reoperation rate compared with other treatment standards of peritonitis
and achieves a low mortality rate in patients with diffuse peritonitis. (Surgery 2000;127:178-84.)
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References
- Multiple organ failure: clinical overview of the syndrome.J Trauma. 1990; 30: 163-165
- Multiple organ failure: pathophysiology and potential future therapy.Ann Surg. 1992; 216: 117-134
- Laparotomy for abdominal sepsis in the critically ill.Br J Surg. 1996; 83: 535-539
- Weitere Erfahrungen über die operative Behandlung der Perforationsperitonitis.Arch Klin Chir (Berl). 1889; 39: 756-784
- A prospective randomized study of continuous peritoneal lavage postoperatively in the treatment of purulent peritonitis.Surg Gynecol Obstet. 1986; 163: 433-436
- The treatment of generalized peritonitis by closed postoperative peritoneal lavage: a critical review of the literature.Arch Surg. 1987; 122: 1005-1010
- Planned relaparotomie vs relaparotomie in the treatment of intra-abdominal infections.Arch Surg. 1995; 130: 1193-1196
- Planned reoperations and open management in critical intra-abdominal infections: prospective experience in 52 cases.World J Surg. 1991; 15: 537-545
- Scheduled reoperation (Etappen-lavage) for diffuse peritonitis.Arch Surg. 1986; 121: 147-152
- “Laparostomy”: a technique for the management of intractable intra-abdominal sepsis.Br J Surg. 1986; 73: 253-259
- Der Mannheimer Peritonitis-Index: Ein Instrument zur intraoperativen Prognose der Peritonitis.Chirurg. 1987; 58: 84-92
- Wertigkeit klinischer Parameter zur Prognosebeurteilung der Peritonitis: Validierung des Mannheimer Peritonitis-Index.Langenbecks Arch Chir. 1994; 379: 152-158
- Prognosis in intra-abdominal infections.Arch Surg. 1996; 131: 641-645
- Prognostic scoring systems to predict outcome in peritonitis and intraabdominal sepsis.Br J Surg. 1997; 84: 1532-1534
- Prediction of outcome using the Mannheim peritonitis index in 2003 patients.Br J Surg. 1994; 81: 209-213
- Guidelines for clinical care: anti-infective agents for intra-abdominal infection.Arch Surg. 1992; 127: 83-89
- Management of intra-abdominal infections: the case for intraoperative cultures and comprehensive broad-spectrum antibiotic coverage.Arch Surg. 1996; 131: 1193-1201
- Minimal antibiotic therapy after emergency abdominal surgery: a prospective study.Br J Surg. 1994; 81: 989-991
- The elusive pathophysiology of the multiple organ failure syndrome.Ann Surg. 1993; 218: 109-110
- Rational antibiotic therapy for intra-abdominal infections.Lancet. 1997; 249: 517-518
- The gastrointestinal tract: the “undrained abscess” of multiple organ failure.Ann Surg. 1993; 218: 111-119
- Management of secondary peritonitis.Ann Surg. 1996; 224: 10-18
- Therapeutic options in peritonitis.Surg Infect. 1994; 74: 677-692
- Principles and limitations of operative management of intraabdominal infections.World J Surg. 1990; 14: 210-217
- Gastrointestinal fistulas associated with large abdominal wall defects: experience with 43 patients.Br J Surg. 1990; 77: 97-100
- Intraperitoneal micro-organisms and the severity of peritonitis.Eur J Surg. 1995; 161: 501-508
- Edotoxinelimination durch intra- und postoperative Lavage bei diffuser bakterieller Peritonitis.Arch Klin Chir. 1988; II ([abstract]) (Berl): 654
- Endotoxin in the peritoneal fluid of bacterial peritonitis.Chir Forum. 1988; : 301-304
- Extensive intraoperative lavage: the key-maneuver in the treatment of severe peritonitis.Dig Surg. 1996; 13: 400-404
- Generalized peritonitis: to irrigate or not to irrigate the abdominal cavity.Arch Surg. 1982; 117: 209-211
- The choice of surgical procedure for peritonitis due to colonic perforation.Arch Surg. 1993; 128: 814-818
- Mechanically assisted intraoperative peritoneal lavage for generalized peritonitis as a result of perforation of the upper part of the gastrointestinal tract.J Am Coll Surg. 1994; 179: 443-448
Article info
Publication history
Accepted:
July 18,
1999
Footnotes
*Reprint requests: M.W. Büchler, MD, Department of Visceral and Transplantation Surgery, University of Bern, Inselspital, CH-3010 Bern, Switzerland.
Identification
Copyright
© 2000 Mosby, Inc. Published by Elsevier Inc. All rights reserved.