Granular cell tumors (gcts) initially were described by Muller in 1836 and by Virchow
and Weber in 1854.
1
Abrikossoff,
2
in 1926, considered GCTs to be of muscular origin and, on the basis of their morphology
and their frequent localization in the tongue, coined the term “myoblastic myomata.”
Feyrter,
3
in 1935, and subsequently, Fust and Custer,
4
in 1949, suggested a neurogenic origin. Since that time, approximately 1000 cases
of GCTs have been reported in the literature under a variety of names that reflect
their controversial histologic cell of origin (eg, granular cell myoblastoma, neuroma,
and schwannoma.)
5
The current literature supports the use of the noncommittal term, granular cell tumor.
The first GCT of the biliary tree was reported at the time of an autopsy in 1952 by
Coggins.
6
Since then, only 57 cases of GCT of the extrahepatic biliary tree have been reported.To read this article in full you will need to make a payment
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References
- Granular cell tumor of the common bile duct.Dig Dis Sci. 1981; 26: 938-942
- Uber myome, ausgehend von der quergestreiften willkurlichen muskulatur.Virchows Arch Pathol Anat. 1926; 260: 215-233
- Uber eine eigenartige geschwulstform des nervengewebes im menschlichen verdanungs schlauch.Virchows Arch Pathol Anat. 1935; 295: 480-501
- On neurogenesis of so-called granular cell myoblastoma.Am J Clin Pathol. 1949; 19: 522-535
- Malignant granular cell tumors: report of a case and review of the literature.Surgery. 1994; 116: 49-54
- Granular cell myoblastoma of the common bile duct: report of a case with autopsy findings.Arch Pathol Lab Med. 1952; 54: 398-402
- S-100 protein in granular cell tumors. (Granular cell myoblastomas).Cancer. 1982; 49: 1834-1838
- Granular cell tumor of the biliary tree. A report of two cases and a review of the literature.Am J Surg Pathol. 1991; 15: 460-465
- Biliary granular cell tumor: a little-known curable bile duct neoplasm of young people.Surgery. 1988; 103: 328-334
- Malignant granular cell tumor: a case report and review of the recent literature.Hum Pathol. 1996; 27: 853-858
- Multicentric granular cell tumor of the colon: report of a patient with 52 tumors.Am J Gastroenterol. 1993; 88: 1785-1787
- Spindle cell tumor of the pancreas: treatment by pancreaticoduodenectomy.Surgery. 1997; 122: 105-111
- Granular cell tumor of the biliary system.Med Pediatr Oncol. 1994; 23: 50-56
- Granular cell tumor of the extrahepatic biliary tract.Am Surg. 1998; 64: 1033-1036
- Granular cell tumor.Ryoikibetsu Shokogun Shirizu. 1996; 9: 259-260
Article info
Publication history
Accepted:
January 12,
2000
Footnotes
*Reprint requests: Stavros Karakozis, MD, Department of Surgery, Room G-253, Washington Hospital Center, 110 Irving St, NW, Washington, DC 20010.
**Surgery 2000;128:113-5.
Identification
Copyright
© 2000 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
