Xenografts are organs or tissues that have been transplanted between different species.
Xenografting—the transplantation of animal organs into humans—offers a potential solution
to the critical shortage of human donor organs for transplantation. One skeptic has
stated: “Xenotransplantation is just around the corner… and it always will be.” However,
recent advances in immunology and genetics have clearly moved this therapy closer
to the bedside than ever before.
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No one has successfully performed a pig-to-human organ transplant yet, but clinical
trials are contemplated in the near future. This article reviews the progress in xenotransplantation
and discusses the problems that remain.To read this article in full you will need to make a payment
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References
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Article info
Publication history
Accepted:
April 29,
2000
Footnotes
☆Reprint requests: David Grant, Toronto General Hospital, 621 University Ave, NU-10-114, Toronto, ON M5G-2c4, Canada.
☆☆Surgery 2001;129:243-7.
★*Dr Levy and Dr Grant are executive officers in Transplantation Technologies, Inc, Toronto, Canada, a private biotechnology company that is studying the problems associated with xenografting.
Identification
Copyright
© 2001 Mosby, Inc. Published by Elsevier Inc. All rights reserved.
