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Original Communications| Volume 132, ISSUE 5, P817-825, November 2002

Recovery after uncomplicated laparoscopic cholecystectomy

      Abstract

      Background. After laparoscopic cholecystectomy, the duration of convalescence is 2 to 3 weeks with an unclear pathogenesis. This study was undertaken to analyze postoperative recovery after uncomplicated elective laparoscopic cholecystectomy. Methods. Twenty-four consecutive unselected employed patients were followed up prospectively from 1 week before to 1 week after outpatient laparoscopic cholecystectomy. Daily computerized monitoring of physical motor activity and sleep duration and night sleep fragmentation (actigraphy), subjective sleep quality, pulmonary function, pain, and fatigue were registered. Treadmill exercise performance (preoperatively and at postoperative days 2 and 8) and nocturnal pulse oximetry at the patients' homes (preoperatively and postoperative nights 1-3) were completed. Results. Median age was 41 years (range, 21-56). Compared with preoperatively, levels of physical motor activity, fatigue, and pain scores were normalized 2 days after operation. Subjective sleep quality was significantly worsened on the first postoperative night, and sleep duration was significantly increased on the first 2 postoperative nights. There were no significant perioperative changes in actigraphy night sleep fragmentation, incidence of self-reported awakenings or nightmares/distressing dreams, exercise performance, or nocturnal oxygenation. Pulmonary peak flow measurements were normalized the day after operation. Conclusion. After uncomplicated outpatient laparoscopic cholecystectomy, there is no pathophysiologic basis for recommending a postoperative convalescence of more than 2 to 3 days in otherwise healthy younger patients. (Surgery 2002;132:817-25.)
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      References

        • Kehlet H
        Surgical stress response: does endoscopic surgery confer an advantage?.
        World J Surg. 1999; 23: 801-807
        • Downs SH
        • Black NA
        • Devlin HB
        • Royston CMS
        • Russell RCG
        Systematic review of the effectiveness and safety of laparoscopic cholecystectomy.
        Ann R Coll Surg Engl. 1996; 78: 241-323
        • Jakeways MS
        • Mitchell V
        • Hashim IA
        • Chadwick SJ
        • Shenkin A
        • Green CJ
        • et al.
        Metabolic and inflammatory responses after open or laparoscopic cholecystectomy.
        Br J Surg. 1994; 81: 127-131
        • Kristiansson M
        • Saraste L
        • Soop M
        • Sundqvist KG
        • Thorne A
        Diminished interleukin-6 and C-reactive protein responses to laparoscopic versus open cholecystectomy.
        Acta Anaesthesiol Scand. 1999; 43: 146-152
        • Rosenberg-Adamsen S
        • Skarbye M
        • Wildschiødtz G
        • Kehlet H
        • Rosenberg J
        Sleep after laparoscopic cholecystectomy.
        Br J Anaesth. 1996; 77: 572-575
        • Delaunay L
        • Bonnet F
        • Cherqui D
        • Rimaniol JM
        • Dahan E
        • Atlan G
        Laparoscopic cholecystectomy minimally impairs postoperative cardiorespiratory and muscle performance.
        Br J Surg. 1995; 82: 373-376
        • Da CM
        • Qureshi MA
        • Brindley NM
        • Burke PE
        • Grace PA
        • Bouchier-Hayes D
        Normal inspiratory muscle strength is restored more rapidly after laparoscopic cholecystectomy.
        Ann R Coll Surg Engl. 1995; 77: 252-255
        • Majeed AW
        • Troy G
        • Nicholl JP
        • Smythe A
        • Reed MW
        • Stoddard CJ
        • et al.
        Randomised, prospective, single-blind comparison of laparoscopic versus small-incision cholecystectomy.
        Lancet. 1996; 347: 989-994
        • Barkun JS
        • Barkun AN
        • Sampalis JS
        • Fried G
        • Taylor B
        • Wexler MJ
        • et al.
        Randomised controlled trial of laparoscopic versus mini cholecystectomy.
        Lancet. 1992; 340 (The McGill Gallstone Treatment Group): 1116-1119
        • McMahon AJ
        • Russell IT
        • Baxter JN
        • Ross S
        • Anderson JR
        • Morran CG
        • et al.
        Laparoscopic versus minilaparotomy cholecystectomy: a randomised trial.
        Lancet. 1994; 343: 135-138
        • Vander VG
        • Shimi SM
        • Cuschieri A
        Outcome after cholecystectomy for symptomatic gall stone disease and effect of surgical access: laparoscopic vs open approach.
        Gut. 1993; 34: 1448-1451
        • Berggren U
        • Gordh T
        • Grama D
        • Haglund U
        • Rastad J
        • Arvidsson D
        Laparoscopic versus open cholecystectomy: hospitalization, sick leave, analgesia and trauma responses.
        Br J Surg. 1994; 81: 1362-1365
        • McGinn FP
        • Miles AJ
        • Uglow M
        • Ozmen M
        • Terzi C
        • Humby M
        Randomized trial of laparoscopic cholecystectomy and mini-cholecystectomy.
        Br J Surg. 1995; 82: 1374-1377
        • McLaughlin GJ
        • Macintyre MC
        Return to work after laparoscopic cholecystectomy.
        Br J Surg. 1995; 82: 239-241
        • Bisgaard T
        • Klarskov B
        • Rosenberg J
        • Kehlet H
        Factors determining convalescence after uncomplicated laparoscopic cholecystectomy.
        Arch Surg. 2001; 136: 917-921
        • Bisgaard T
        • Klarskov B
        • Rosenberg J
        • Kehlet H
        Characteristics and prediction of early pain after laparoscopic cholecystectomy.
        Pain. 2001; 90: 261-269
        • Bisgaard T
        • Klarskov B
        • Kristiansen VB
        • Callesen T
        • Schulze S
        • Kehlet H
        • et al.
        Multi-regional local anesthetic infiltration during laparoscopic cholecystectomy in patients receiving prophylactic multi-modal analgesia: a randomized, double-blinded, placebo-controlled study.
        Anesth Analg. 1999; 89: 1017-1024
        • Bisgaard T
        • Kjærsgaard M
        • Bernhard A
        • Kehlet H
        • Rosenberg J
        Computerized monitoring of physical activity and sleep in postoperative abdominal surgery patients.
        J Clin Monitor Comput. 1999; 15: 1-8
        • Patterson SM
        • Krantz DS
        • Montgomery LC
        • Deuster PA
        • Hedges SM
        • Nebel LE
        Automated physical activity monitoring: validation and comparison with physiological and self-report measures.
        Psychophysiology. 1993; 30: 296-305
        • Redeker NS
        • Mason DJ
        • Wykpisz E
        • Glica B
        Sleep patterns in women after coronary artery bypass surgery.
        Appl Nurs Res. 1996; 9: 115-122
        • Kjærsgaard M
        • Lie C
        • Bisgaard T
        • Kehlet H
        • Rosenberg J
        Effect of oxygen on postoperative cardiovascular response to exercise.
        Eur J Surg. 2000; 166: 915-919
        • Rosenberg J
        • Rasmussen V
        • von Jessen F
        • Ullstad T
        • Kehlet H
        Late postoperative episodic and constant hypoxaemia and associated ECG abnormalities.
        Br J Anaesth. 1990; 65: 684-691
        • Christensen T
        • Bendix T
        • Kehlet H
        Fatigue and cardiorespiratory function following abdominal surgery.
        Br J Surg. 1982; 69: 417-419
        • Kehlet H
        Multimodal approach to control postoperative pathophysiology and rehabilitation.
        Br J Anaesth. 1997; 78: 606-617
        • Bisgaard T
        • Kehlet H
        • Rosenberg J
        Pain and convalescence after laparoscopic cholecystectomy.
        Eur J Surg. 2001; 167: 84-96
        • Johnson A
        Laparoscopic surgery.
        Lancet. 1997; 349: 631-635
        • Tryon WW
        Activity measurement in psychology and medicine.
        in: : Plenum Press, New York1991: 1-247
        • Redeker NS
        • Mason DJ
        • Wykpisz E
        • Glica B
        • Miner C
        First postoperative week activity patterns and recovery in women after coronary artery bypass surgery.
        Nurs Res. 1994; 43: 168-173
        • Åkerstedt T
        • Hume K
        • Minors D
        • Waterhouse J
        The meaning of good sleep: a longitudinal study of polysomnography and subjective sleep quality.
        J Sleep Res. 1994; 3: 152-158
        • Lockley SW
        • Skene DJ
        • Arendt J
        Comparison between subjective and actigraphic measurement of sleep and sleep rhythms.
        J Sleep Res. 1999; 8: 175-183
        • Cole RJ
        • Kripke DF
        • Gruen W
        • Mullaney DJ
        • Gillin JC
        Automatic sleep/wake identification from wrist activity.
        Sleep. 1992; 15: 461-469
        • Christensen T
        • Stage JG
        • Galbo H
        • Christensen NJ
        • Kehlet H
        Fatigue and cardiac and endocrine metabolic response to exercise after abdominal surgery.
        Surgery. 1989; 105: 46-50
        • Christensen T
        • Kehlet H
        Postoperative fatigue.
        World J Surg. 1993; 17: 220-225
        • Spath-Schwalbe E
        • Hansen K
        • Schmidt F
        • Schrezenmeier H
        • Marshall L
        • Burger K
        • et al.
        Acute effects of recombinant human interleukin-6 on endocrine and central nervous sleep functions in healthy men.
        J Clin Endocrinol Metab. 1998; 83: 1573-1579
        • Rosenberg-Adamsen S
        • Kehlet H
        • Dodds C
        • Rosenberg J
        Postoperative sleep disturbances: mechanisms and clinical implications.
        Br J Anaesth. 1996; 76: 552-559
        • Troidl H
        • Spangenberger W
        • Langen R
        • Al-Jaziri A
        • Eypasch E
        • Neugebauer E
        • et al.
        Laparoscopic cholecystectomy: technical performance, safety and patient's benefit.
        Endoscopy. 1992; 24: 252-261