Advertisement
Images in surgery| Volume 135, ISSUE 4, P455-456, April 2004

Leiomyosarcoma of the portal venous system: A case report and review of literature

  • Angel Celdrán
    Correspondence
    Reprint requests: A. Celdrán, MD, Department of Surgery, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Av Reyes Católicos, n° 2, 28040 Madrid, Spain.
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
  • Octavio Frieyro
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
  • Antonio del Rı́o
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
  • Angeles Franco
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
  • Orencio Bosch
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
  • Jose Luis Sarasa
    Affiliations
    From the Departments of General Surgery, Vascular Surgery, Radiology, Gastroenterology, and Pathology, Clı́nica “Nuestra Señora de la Concepción,” Fundación Jiménez Dı́az, Madrid, Spain
    Search for articles by this author
      A 66-year-old man was admitted to the hospital with epigastric pain radiating bilaterally to the back. The patient's history was significant for smoking, prior ethanol abuse, hypertension, and colonic polypectomy for benign tubular adenoma. Physical examination did not show any pathologic signs except epigastric pain to superficial and deep abdominal palpation. Peripheral blood count and biochemical test results were normal. A sonogram showed a mass over the mesenteric vein. Abdominal computed tomography confirmed the sonographic findings of a 4-cm lobulated mass arising from the mesenteric vein with necrotic areas. The duodenal wall and the superior mesenteric artery were not affected (Fig 1). Laparotomy confirmed a lobulated tumor arising from the anterior wall of the superior mesenteric vein caudal to the portal vein, superior mesenteric vein confluence, and proximal to the initial secondary mesenteric venous branch. The tumor also grew in the right colonic mesentery along the medial colic vessels. The segment of superior mesenteric and portal veins containing the tumor was isolated by sectioning the first secondary mesenteric veins and the medial colic vessels in the mesocolon (Fig 2). The tumor was resected, and mesenteric venous flow was restored through an autogenous saphenous vein interposition graft. A right hemicolectomy was performed for colonic ischemia recognized after ligation of the middle colic vein. The postoperative course was uneventful. On cut section, the tumor showed homogeneous firm white tissue, and microscopically, it was made up of interlacing bundles of neoplastic smooth muscle fibers infiltrating the wall of the mesenteric vein without involving surgical margins. The nuclei were elongated, with hypercromasia and variation in size and shape, and 18 mitoses were counted in 10 high-power fields. Superior mesenteric vein graft patency was confirmed with abdominal computed tomography 6 months after surgery.
      Figure thumbnail gr1
      Fig 1Computed tomographic scan image with contrast enhancement shows well-defined nodular tumor (between arrows) involving superior mesenteric vein and narrowing its lumen.
      Figure thumbnail gr2
      Fig 2Tumor view from its right side after isolation from mesentery. MV, Mesenteric vein; PV, portal vein.
      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'

      Subscribe:

      Subscribe to Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect

      References

        • Kevorkian J.
        • Centro D.P.
        Leiomyosarcoma of large arteries and veins.
        Surgery. 1973; 73: 390-400
        • Puig-Sureda J.
        • Gallart-Esquerdo A.
        • Roca de Viñals R.
        • Salleras V.
        Leiomiosarcoma de la vena cólica inferior.
        Medicina Clı́nica. 1947; VIII: 2
        • Choquart P.
        • Leclerc J.-P.
        • Modigliani R.
        • Celerier M.
        • Dubost C.
        • Manoux D.
        Leiomyosarcome de la veine mesenterique inferieure.
        Ann Chir. 1976; 30: 161-163
        • Wilson S.R.
        • Hine A.L.
        Leiomyosarcoma of the portal vein.
        AJR Am J Roentgenol. 1987; 149: 183-184
        • McFadden D.W.
        • Hiyama D.
        Primary mesenteric leimyosarcoma masquerading as a pancreatic pseudocyst.
        Pancreas. 1993; 8 ([letter]): 647-649