Hyperparathyroidism caused by a solitary parathyroid adenoma or multigland disease can occur in association with other malignancies. Parathyroid hyperplasia occurs in association with pancreatic endocrine tumors or medullary thyroid carcinoma in patients with MEN 1 or MEN 2, respectively. Occasionally patients with hyperparathyroidism can present with synchronous or metachronous malignancies, most commonly well-differentiated thyroid carcinoma, renal cell carcinoma, and bladder cancer. An association between hyperparathyroidism and polycythemia vera has been described,
1.and there is a suggestion that surgical cure of the hyperparathyroidism may induce remission of the myeloproliferative disorder. We describe a patient who demonstrated a significant improvement in polycythemia after successful parathyroidectomy.
- Berlin R.
Primary hyperplasia of parathyroid glands associated with ulcers in the oesophagus and duodenum and polycythemia of splenomegalic type.
Acta Med Scand. 1949; 135: 18-24
To read this article in full you will need to make a payment
Purchase one-time access:Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
One-time access price info
- For academic or personal research use, select 'Academic and Personal'
- For corporate R&D use, select 'Corporate R&D Professionals'
Subscribe:Subscribe to Surgery
Already a print subscriber? Claim online access
Already an online subscriber? Sign in
Register: Create an account
Institutional Access: Sign in to ScienceDirect
- Primary hyperplasia of parathyroid glands associated with ulcers in the oesophagus and duodenum and polycythemia of splenomegalic type.Acta Med Scand. 1949; 135: 18-24
- Parathyroid adenomas and malignant neoplasms: coincidence or etiological association?.Adv Clin Path. 1997; 1: 275-280
- Renal polycythemia. Case of primary hyperparathyroidism associated with nephrocalcinosis and erythrocytosis.Acta Med Scand. 1961; 170: 191-194
- Parathyroid carcinoma associated with polycythemia vera.Bone. 1991; 12: 237-239
- An unusual cause of hypercalcemia in polycythemia vera: parathyroid adenoma.Acta Med Okayama. 2002; 56: 167-170
- Polycythemia vera and primary hyperparathyroidism.Arch Intern Med. 1981; 141: 951-953
- Primary hyperparathyroidism associated with pancytosis.N Engl J Med. 1985; 313: 187
Accepted: May 11, 2004Philadelphia, Pa
© 2005 Elsevier Inc. Published by Elsevier Inc. All rights reserved.